Manfredonia is the nephew of director
Luigi Comencini. After working on several films as assistant director to
Antonio Albanese, Luigi Comencini, and
Cristina Comencini, Manfredonia made his debut as director in 2001 with the comedy
Se fossi in te (If I Were You). He followed this in 2004 with
È già ieri (It's Already Yesterday), a remake of the 1993 American comedy
Groundhog Day, with Antonio Albanese reprising Bill Murray's role. In 2008, he directed
We Can Do That. In 2011, 2012, and 2019, he worked with Albanese again in the films
Qualunquemente (Whatever),
Tutto tutto niente niente (Everything Everything Nothing Nothing), and ''Cetto c'è, senzadubbiamente'' (It's Cetto, Without a Doubt) respectively. ==Filmography==