Reynolds did her undergraduate studies at
Yankton College and was encouraged by the head of the mathematics department there to go on to graduate study. She earned a master's degree in statistics at
Virginia Tech, and joined the CDC in 1960. Five years later, she moved to
Emory University as an instructor, and completed a Ph.D. there in 1973. Her dissertation,
A Control Model for Gonorrhea, was one of the first works to produce a mathematical model for the sexual transmission of disease. She returned to CDC, where she headed the Evaluation and Statistical Services Branch of the Division of Sexually Transmitted Diseases from 1979 to 1989, and worked in the
Office of Minority Health as a senior statistician from 1989 to 2007, when she retired. She also chaired the Statistics in Epidemiology section of the
American Statistical Association. ==Activism==