Motion perception

The inability to perceive motion is called akinetopsia and it may be caused by a lesion to cortical area V5 in the extrastriate cortex. Neuropsychological studies of a patient who could not see motion, seeing the world in a series of static "frames" instead, suggested that visual area V5 in humans is homologous to motion processing area V5/MT in primates. ==First-order motion perception==

, in which a succession of different positions gives the illusion of a moving ball When two or more stimuli are alternatively switched on and off, they can produce two distinct motion perceptions. The first, known as beta movement, is demonstrated in the yellow-ball figure and forms the basis for electronic news ticker displays. However, at faster alternation rates, and when the distance between the stimuli is optimal, an illusory "object"—matching the background color—appears to move between the stimuli, alternately occluding them. This phenomenon is called the phi phenomenon and is often described as an example of "pure" motion detection, uncontaminated by form cues, unlike beta movement. motion-energy sensors, or Elaborated Reichardt Detectors. These sensors are described as detecting motion by spatio-temporal correlation and are considered by some to be plausible models for how the visual system may detect motion. (Although, again, the notion of a "pure motion" detector suffers from the problem that there is no "pure motion" stimulus, i.e. a stimulus lacking perceived figure/ground properties). There is still considerable debate regarding the accuracy of the model and exact nature of this proposed process. It is not clear how the model distinguishes between movements of the eyes and movements of objects in the visual field, both of which produce changes in luminance on points on the retina. ==Second-order motion perception==

Second-order motion is when the moving contour is defined by contrast, texture, flicker or some other quality that does not result in an increase in luminance or motion energy in the Fourier spectrum of the stimulus. There is much evidence to suggest that early processing of first- and second-order motion is carried out by separate pathways. Second-order mechanisms have poorer temporal resolution and are low-pass in terms of the range of spatial frequencies to which they respond. (The notion that neural responses are attuned to frequency components of stimulation suffers from the lack of a functional rationale and has been generally criticized by G. Westheimer (2001) in an article called "The Fourier Theory of Vision.") Second-order motion produces a weaker motion aftereffect unless tested with dynamically flickering stimuli. ==The aperture problem==

appears to be moving down and to the right, perpendicular to the orientation of the bars. But it could be moving in many other directions, such as only down, or only to the right. It is impossible to determine unless the ends of the bars become visible in the aperture. The motion direction of a contour is ambiguous, because the motion component parallel to the line cannot be inferred based on the visual input. This means that a variety of contours of different orientations moving at different speeds can cause identical responses in a motion sensitive neuron in the visual system. ==Motion integration==

Some have speculated that, having extracted the hypothesized motion signals (first- or second-order) from the retinal image, the visual system must integrate those individual local motion signals at various parts of the visual field into a 2-dimensional or global representation of moving objects and surfaces. (It is not clear how this 2D representation is then converted into the perceived 3D percept) Further processing is required to detect coherent motion or "global motion" present in a scene. The ability of a subject to detect coherent motion is commonly tested using motion coherence discrimination tasks. For these tasks, dynamic random-dot patterns (also called random dot kinematograms) are used that consist in 'signal' dots moving in one direction and 'noise' dots moving in random directions. The sensitivity to motion coherence is assessed by measuring the ratio of 'signal' to 'noise' dots required to determine the coherent motion direction. The required ratio is called the motion coherence threshold. ==Motion in depth==

As in other aspects of vision, the observer's visual input is generally insufficient to determine the true nature of stimulus sources, in this case their velocity in the real world. In monocular vision for example, the visual input will be a 2D projection of a 3D scene. The motion cues present in the 2D projection will by default be insufficient to reconstruct the motion present in the 3D scene. Put differently, many 3D scenes will be compatible with a single 2D projection. The problem of motion estimation generalizes to binocular vision when we consider occlusion or motion perception at relatively large distances, where binocular disparity is a poor cue to depth. This fundamental difficulty is referred to as the inverse problem. Nonetheless, some humans do perceive motion in depth. There are indications that the brain uses various cues, in particular temporal changes in disparity as well as monocular velocity ratios, for producing a sensation of motion in depth. Two different binocular cues of the perception motion in depth are hypothesized: Inter-ocular velocity difference (IOVD) and changing disparity (CD) over time. Motion in depth based on inter-ocular velocity differences can be tested using dedicated binocularly uncorrelated random-dot kinematograms. Study results indicate that the processing of these two binocular cues – IOVD and CD – may use fundamentally different low-level stimulus features, which may be processed jointly that later stages. Additionally, as monocular cue, also the changing size of retinal images contributes to motion in depth detection. ==Perceptual learning of motion==

Detection and discrimination of motion can be improved by training with long-term results. Participants trained to detect the movements of dots on a screen in only one direction become particularly good at detecting small movements in the directions around that in which they have been trained. This improvement was still present 10 weeks later. However perceptual learning is highly task and stimulus specific. For motion-direction specific tasks, participants that trained on tasks on one motion direction showed improved performance of the same task, within certain range of the trained direction. This range narrows for harder task and widens for harder tasks. However, improvement on one specific motion task does not always improve performances on other motion taks, or for other sorts of stimuli. ==Cognitive map==

A cognitive map is a type of mental representation which serves an individual to acquire, code, store, recall, and decode information about the relative locations and attributes of phenomena in their spatial environment. Place cells work with other types of neurons in the hippocampus and surrounding regions of the brain to perform this kind of spatial processing, but the ways in which they function within the hippocampus are still being researched. Many species of mammals can keep track of spatial location even in the absence of visual, auditory, olfactory, or tactile cues, by integrating their movements—the ability to do this is referred to in the literature as path integration. A number of theoretical models have explored mechanisms by which path integration could be performed by neural networks. In most models, such as those of Samsonovich and McNaughton (1997) or Burak and Fiete (2009), the principal ingredients are (1) an internal representation of position, (2) internal representations of the speed and direction of movement, and (3) a mechanism for shifting the encoded position by the right amount when the animal moves. Because cells in the Medial Entorhinal Cortex (MEC) encode information about position (grid cells) and movement (head direction cells and conjunctive position-by-direction cells), this area is currently viewed as the most promising candidate for the place in the brain where path integration occurs. ==Neurophysiology==

Motion sensing using vision is crucial for detecting a potential mate, prey, or predator, and thus it is found both in vertebrates and invertebrates vision throughout a wide variety of species, although it is not universally found in all species. In vertebrates, the process takes place in retina and more specifically in retinal ganglion cells, which are neurons that receive input from bipolar cells and amacrine cells on visual information and process output to higher regions of the brain including, thalamus, hypothalamus, and mesencephalon. The study of directionally selective units began with a discovery of such cells in the cerebral cortex of cats by David Hubel and Torsten Wiesel in 1959. Following the initial report, an attempt to understand the mechanism of directionally selective cells was pursued by Horace B. Barlow and William R. Levick in 1965. Their in-depth experiments in rabbit's retina expanded the anatomical and physiological understanding of the vertebrate visual system and ignited the interest in the field. Numerous studies that followed thereafter have unveiled the mechanism of motion sensing in vision for the most part. Alexander Borst and Thomas Euler's 2011 review paper, "Seeing Things in Motion: Models, Circuits and Mechanisms". discusses certain important findings from the early discoveries to the recent work on the subject, coming to the conclusion of the current status of the knowledge. Direction selective (DS) cells Direction selective (DS) cells in the retina are defined as neurons that respond differentially to the direction of a visual stimulus. According to Barlow and Levick (1965), the term is used to describe a group of neurons that "gives a vigorous discharge of impulses when a stimulus object is moved through its receptive field in one direction." ON/OFF DS ganglion cells ON/OFF DS ganglion cells act as local motion detectors. They fire at the onset and offset of a stimulus (a light source). If a stimulus is moving in the direction of the cell's preference, it will fire at the leading and the trailing edge. Their firing pattern is time-dependent and is supported by the Reichardt-Hassenstain model, which detects spatiotemporal correlation between the two adjacent points. The detailed explanation of the Reichardt-Hassenstain model will be provided later in the section. The anatomy of ON/OFF cells is such that the dendrites extend to two sublaminae of the inner plexiform layer and make synapses with bipolar and amacrine cells. They have four subtypes, each with its own preference for direction. ON DS ganglion cells Unlike ON/OFF DS ganglion cells that respond both to the leading and the trailing edge of a stimulus, ON DS ganglion cells are responsive only to a leading edge. The dendrites of ON DS ganglion cells are monostratified and extend into the inner sublamina of the inner plexiform layer. They have three subtypes with different directional preferences. OFF DS ganglion cells OFF DS ganglion cells act as a centripetal motion detector, and they respond only to the trailing edge of a stimulus. They are tuned to upward motion of a stimulus. The dendrites are asymmetrical and arbor in to the direction of their preference. This is a model used to detect correlation between the two adjacent points. It consists of two symmetrical subunits. Both subunits have a receptor that can be stimulated by an input (light in the case of visual system). In each subunit, when an input is received, a signal is sent to the other subunit. At the same time, the signal is delayed in time within the subunit, and after the temporal filter, is then multiplied by the signal received from the other subunit. Thus, within each subunit, the two brightness values, one received directly from its receptor with a time delay and the other received from the adjacent receptor, are multiplied. The multiplied values from the two subunits are then subtracted to produce an output. The direction of selectivity or preferred direction is determined by whether the difference is positive or negative. The direction which produces a positive outcome is the preferred direction. In order to confirm that the Reichardt-Hassenstein model accurately describes the directional selectivity in the retina, the study was conducted using optical recordings of free cytosolic calcium levels after loading a fluorescent indicator dye into the fly tangential cells. The fly was presented uniformly moving gratings while the calcium concentration in the dendritic tips of the tangential cells was measured. The tangential cells showed modulations that matched the temporal frequency of the gratings, and the velocity of the moving gratings at which the neurons respond most strongly showed a close dependency on the pattern wavelength. This confirmed the accuracy of the model both at the cellular and the behavioral level. Although the details of the Hassenstein-Reichardt model have not been confirmed at an anatomical and physiological level, the site of subtraction in the model is now being localized to the tangential cells. When depolarizing current is injected into the tangential cell while presenting a visual stimulus, the response to the preferred direction of motion decreased, and the response to the null direction increased. The opposite was observed with hyperpolarizing current. The T4 and T5 cells, which have been selected as a strong candidate for providing input to the tangential cells, have four subtypes that each project into one of the four strata of the lobula plate that differ in the preferred orientation. Neural mechanism: starburst amacrine cells The direction selective (DS) ganglion cells receive inputs from bipolar cells and starburst amacrine cells. The DS ganglion cells respond to their preferred direction with a large excitatory postsynaptic potential followed by a small inhibitory response. On the other hand, they respond to their null direction with a simultaneous small excitatory postsynaptic potential and a large inhibitory postsynaptic potential. Starburst amacrine cells have been viewed as a strong candidate for direction selectivity in ganglion cells because they can release both GABA and Ach. Their dendrites branch out radiantly from a soma, and there is a significant dendritic overlap. Optical measurements of Ca2+ concentration showed that they respond strongly to the centrifugal motion (the outward motion from the soma to the dendrites), while they don't respond well to the centripetal motion (the inward motion from the dendritic tips to the soma). When the starburst cells were ablated with toxins, direction selectivity was eliminated. Moreover, their release of neurotransmitters itself, specifically calcium ions, reflect direction selectivity, which may be presumably attributed to the synaptic pattern. The branching pattern is organized such that certain presynaptic input will have more influence on a given dendrite than others, creating a polarity in excitation and inhibition. Further evidence suggests that starburst cells release inhibitory neurotransmitters, GABA onto each other in a delayed and prolonged manner. This accounts for the temporal property of inhibition. Recent research (published March 2011) relying on serial block-face electron microscopy (SBEM) has led to identification of the circuitry that influences directional selectivity. This new technique provides detailed images of calcium flow and anatomy of dendrites of both starburst amacrine (SAC) and DS ganglion cells. By comparing the preferred directions of ganglion cells with their synapses on SAC's, Briggman et al. provide evidence for a mechanism primarily based on inhibitory signals from SAC's based on an oversampled serial block-face scanning electron microscopy study of one sampled retina, that retinal ganglion cells may receive asymmetrical inhibitory inputs directly from starburst amacrine cells, and therefore computation of directional selectivity also occurs postsynaptically. Such postsynaptic models are unparsimonious, and so if any given starburst amacrine cells conveys motion information to retinal ganglion cells then any computing of 'local' direction selectivity postsynaptically by retinal ganglion cells is redundant and dysfunctional. An acetylcholine (ACh) transmission model of directionally selective starburst amacrine cells provides a robust topological underpinning of a motion sensing in the retina. == See also ==