An early stage appearance was in the long-running farce
Good Night, Ladies at Chicago's
Blackstone Theatre, starring
Buddy Ebsen, which opened on April 12, 1942. Grahame made her
Broadway debut on December 6, 1943, at the
Royale Theatre as Florrie in
Nunnally Johnson's ''
The World's Full of Girls'', which was adapted from
Thomas Bell's 1943 novel
Till I Come Back to You. She was signed to a contract with
MGM Studios under her professional name after
Louis B. Mayer saw her performance. Another Broadway role was in April-May 1944's
Highland Fling. She made her film debut in
Blonde Fever (1944) and then achieved one of her most widely praised roles as the vixenish Violet Bick, saved from disgrace by
George Bailey in ''
It's a Wonderful Life'' (1946). MGM felt unable to develop her potential as a star, and her contract was sold to
RKO Studios in 1947. in
In a Lonely Place (1950)Grahame starred with
Humphrey Bogart in the film
In a Lonely Place (1950) for
Columbia Pictures, a performance for which she gained praise. Though today it is considered among her finest performances, it was not a box-office hit, and
Howard Hughes, owner of RKO, admitted that he never saw it. When she asked to be lent out for roles in
Born Yesterday (also 1950) and
A Place in the Sun (1951), Hughes refused and instead made her perform a supporting role in
Macao (1952). '' (1952) Despite appearing for only a little over nine minutes on screen, she won the
Academy Award for Best Supporting Actress in MGM's
The Bad and the Beautiful (also 1952); she long held the record for the shortest performance on screen to win an acting Oscar until
Beatrice Straight won for
Network (1976) with a five-minute performance. Grahame's career began to wane after her performance in the musical film
Oklahoma! (1955). She, whom audiences were used to seeing as a film noir siren, was viewed by some critics to be miscast as an ignorant country lass in a wholesome musical, and the paralysis of her upper lip from plastic surgery altered her speech and appearance. Additionally, she was rumored to have been difficult on the set of
Oklahoma!, upstaging some of the cast and alienating her co-stars. Grahame also guest-starred in television series, including the science-fiction series
The Outer Limits. In the 1964 episode of that series titled "
The Guests", Grahame plays a forgotten film star living in the past. She also appears in an episode of
The Fugitive ("The Homecoming", 1964) and an episode of ''
Burke's Law'' ("Who Killed The Rabbit's Husband", 1965). Grahame can be seen also in a 1970 episode of
Mannix titled “Duet for Three” (season four, episode 13) and in small roles in the miniseries
Rich Man, Poor Man and
Seventh Avenue. ==Personal life==