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Granulomatous prostatitis

Granulomatous prostatitis is an uncommon disease of the prostate, an exocrine gland of the male reproductive system. It is a form of prostatitis, resulting from infection, BCG vaccine, malacoplakia or systemic granulomatous diseases which involve the prostate.

Pathogenesis
Prostatic secretions escape into the stroma and elicit an inflammatory response. == Histopathology ==
Histopathology
Noticeable destruction of Acini, surrounded by epitheloid cells, giant cells, lymphocytes, plasma cells and dense fibrosis. ==Mimicry of prostate cancer==
Mimicry of prostate cancer
Granulomatous prostatitis can be mistaken for prostate cancer, including on rectal examination, MRI, and heightened PSA scores. A biopsy differentiates. ==Causes==
Causes
Some 70% of cases are idiopathic. Causes may include infection and immunological links. ==Prevalence==
Prevalence
One study stated prevalence in 0.44% in routine prostatectomy specimens, 0.29% in needle biopsies, and 0.77% of TURP, simple prostatectomy, and needle biopsy. ==References==
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