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Gregorio Aglipay (1860–1940), Filipino revolutionary and first supreme bishop of the Philippine Independent Church •
Gregorio Conrado Álvarez (1925–2016), Uruguayan army general and de facto President of Uruguay from 1981 until 1985 •
Gregorio Álvarez (historian) (1889–1986), Argentine historian, physician and writer •
Gregorio S. Araneta (1869–1930), Filipino lawyer, businessman and nationalist •
Gregorio Benito (1946–2020), Spanish retired footballer •
Gregorio C. Brillantes, Filipino writer •
Gregorio di Cecco (c. 1390–after 1424), Italian painter •
Gregório Nunes Coronel (c. 1548–c. 1620), Portuguese theologian, writer and preacher •
Gregorio Cortez (1875–1916), Mexican-American tenant farmer and folk hero •
Gregorio De Gregori (), printer in Renaissance Venice •
Gregorio del Pilar (1875–1899), Philippine Revolutionary Forces general during the Philippine Revolution and the Philippine–American War •
Gregorio De Ferrari (c. 1647–1726), Italian painter •
Gregorio López y Fuentes (1895–1966), Mexican novelist, poet and journalist •
Gregorio López (handballer) (1951–1987), Spanish handball player •
Gregorio López (jurist) (1496–1560), president of the Council of the Indies •
Gregorio López-Bravo y Castro (1923–1985), Spanish politician, Minister of Foreign Affairs between 1969 and 1973 •
Gregorio Luperón (1839–1897), Dominican military and political leader, President of the Dominican Republic from 1879 to 1880 •
Gregorio Marañón (1887–1960), Spanish physician, scientist, historian, writer and philosopher •
Gregório de Matos (1636–1696), colonial Brazilian poet •
Gregorio Pérez (born 1948), Uruguayan football manager and former player •
Gregorio Petit (born 1984), Major League Baseball player from Venezuela •
Gregorio Ricci-Curbastro (1853–1925), Italian mathematician, inventor of tensor calculus •
Gregorio Rodríguez (footballer) (born 2000), Argentine footballer •
Gregorio Salvador Caja (1927-2020), Spanish linguist •
Gregorio Manuel Salvador (born 1981), Equatoguinean footballer ==Surname==