Panionios In 2000, Makos signed for
Panionios from
Ilioupoli at the age of 13. After impressing in the youth academy, he was eventually called up to the
Greece national football team in 2003 and made his debut in a match against
Proodeftiki on 23 May 2004. Makos scored his first goal for Panionios on 1 October 2005, against
Levadiakos. And his first ever European goal vs Bordeaux on 20 December 2007. He was appointed captain in 2006 at the age of 19. During his time at the club, he had become one of Panionios' most important players making over 100 appearances for the club at the young age of 21 and guiding them to successive fifth-place finishes. His impressive performances attracted interest from the "
big three" of Greece and also from teams abroad. In the end Makos agreed to join
AEK Athens.
AEK Athens On 24 June 2009,
AEK signed Makos for €800,000 from Panionios signing a five-year deal with the Athenian club. Soon after signing, Makos stated "
One of the main reasons I decided to come here is because of Dušan Bajević". On 6 July, Makos decided to continue using the number 14 at AEK, a number which he has used since his youth career. On 20 August, Makos made his official debut for AEK, in the game versus
Vaslui in the
Europa League. Makos made his league debut in the 0–1 away win over
Atromitos on 30 August. An unconvincing pre-season and start to the season seen Makos dropped from the starting 11 to the bench. In his first season at AEK, Makos made a total of 28 appearances, 21 in the league, one in the
cup, and six in
Europe. The 2010–11 season started well for Makos. He impressed in the away victory against
Dundee United for the
Europa League play-offs, as well as making good appearances in the pre-season friendlies. Makos continued his fine form throughout the regular season, cementing his place in the AEK first team, and won applause from AEK fans for his passionate tireless displays. In a season mired with disappointing displays for the team, Makos was one of few players who escaped criticism from AEK fans. Overall, his performances were much-improved over his first season at AEK, which was largely deemed as mediocre. The season ended in success as Makos won his first ever piece of silverware, the
2010–11 Greek Cup. Makos kicked off his third season in superb form, scoring his first ever goal for AEK Athens in the season opener in a 1–0 win against
Ergotelis on 18 September 2011. Due to his impressive performances, Makos became a regular in the Greece national team and played against
Israel,
Romania,
Croatia and
Latvia strengthening his chances of getting called up to the final squad for
UEFA Euro 2012 having missed out on the
2010 FIFA World Cup. On 8 May 2012, Makos scored his second goal for AEK against
Panathinaikos in the
Super League Greece play off in the 2–0 home win over their archrivals. At the end of his third season at AEK, Makos made 34 appearances in total, 28 in the league, one in the cup, and five in Europe.
1860 Munich On 9 July 2012 Makos signed a two-year deal with German side
TSV 1860 München for the transfer fee thought to be in the region of €465,000. The German side announced the signing through website, while also shedding light on the finances of the transfer.
AEK are set to receive a reported €465,000. However, Makos will receive €165,000 of that sum as a result of unpaid wages dating back to the start of last season. Makos, 25, was presented to the media on Tuesday as the
2. Bundesliga side finally put end to speculation of a Munich move for Makos that dated back to last month. The German side were also interested in Makos' services back when the Greek international was part of
Panionios.
TSV 1860 München, yet another cash-strapped club, were keen to bringing Makos to Germany during the summer of 2009 but were beaten by
AEK in a bidding war for Makos' services. In 1860 Munich Makos met his former teammate in AEK Athens,
Ismael Blanco. He was given the number 21. He made 11 goalless appearances for
2.Bundesliga.
Anorthosis Famagusta On 5 July 2013, Grigoris Makos signed a two-year contract with
Anorthosis. According to the Cypriot press, Makos' verbal agreement with
Anorthosis is based on a salary of €100,000 per season but will only come to fruition should a deal between the two clubs be finalized.
Anorthosis are scheduled to compete in the
UEFA Europa League 2nd Qualifying Round. Makos, who has signed a two-year deal, has become the second high-profile Greek to join the club since
Traianos Dellas linked up with the then Cypriot champions back in 2008, helping them reach the group stages of the Champions League.
"This is an excellent opportunity for me because my confidence has returned especially with the new coach", he told the club's official website.
"He [coach Christakis Kassianos] has put his trust in me. I am sure I will return to my best here. I will give my all to help the team in the Europa League and then win my place back in the Greek national team". On 16 May 2015, he scored his first goal with the club, in a 3–1 home win against
Apollon Limassol for the Cypriot First Division. At the end of 2014/15 season, Grigoris Makos seem to wish to return to Greece for personal reasons, but did not close the door to
Anorthosis. The management of the club will submit a formal proposal and will make the effort to keep him although it is not easy.
Panetolikos On 3 July 2015, Makos signed a two-year contract with
Panetolikos F.C. From the very beginning he became a leader midfielder for the club. On 3 December 2016, he scored his first goal with the club in a 1–1 away draw against
Veria. On 18 January 2017, after an excellent match at Agrinio,
Panetolikos won 3–2
AEK, with the international defensive midfielder scoring a
brace, for first time in his career, against his former club. At the end of the
2016–17 season, he settled his contract with the club.
Trikala On 14 January 2018, after six months as a free agent, Makos signed a contract with
Football League club
Trikala F.C. Kallithea Makos joined
Gamma Ethniki club
Kallithea FC on 21 September 2018. On 30 January 2019 it was announced, that Makos had left the club.
Kalamata Makos was a free agent for six months, then joined
Gamma Ethniki club
Kalamata on 15 July 2019 on a year contract for an undisclosed fee. ==International career==