Orlov had a quick wit, a fairly accurate appreciation of current events, and was a useful and sympathetic counselor during the earlier portion of Catherine's reign. He entered with enthusiasm, from both patriotic and economic motives, into the question of the improvement of the condition of the
serfs and their partial emancipation. He also led the investigation of
Lieutenant Vasily Mirovich, who tried to free the former Russian Emperor
Ivan VI Antonovich from the
Shlisselburg Fortress (1764). Commander with the rank of Lieutenant Colonel of the
Life Guard Horse Regiment (1764–83), chief of the
Chevalier Guard Regiment – the Empress's personal guard (1765–83). As the president of the
Free Economic Society, he was also their most prominent advocate in
the great commission of 1767, though he aimed primarily at pleasing the empress, who affected great liberality in her earlier years. He promoted smallpox inoculation and was one of the first in Russia to inoculate against
smallpox together with Empress Catherine II in 1768. He was one of the earliest
propagandists of the
Slavophile idea of the emancipation of the Christians from
Ottoman rule. During the
Russo-Turkish War of 1768–74, he convinced Catherine to send the
Navy at the
Mediterranean, and was involved in the formation and dispatch of artillery teams to the front. In 1771, he was sent as first Russian
plenipotentiary to the peace congress of
Focşani, but he failed in his mission, owing partly to the obstinacy of the Ottomans, and partly (according to Panin) to his own outrageous insolence. In 1771 in Moscow he stopped the spread of the plague epidemic, which caused a "
Plague Riot" in the city, stopped looting, opened hospitals and orphanages. ==Fall==