Guo Quanbo was born in
Tianmen,
Hubei. He joined
Chinese Super League side
Beijing Guoan's youth academy at the age of 8 in 2005 when traveling to Beijing with his family. He was promoted to Beijing Sinobo Guoan's first team squad by manager
José González in 2017. On 19 May 2018, he made his senior debut in a 2–0 away win over
Changchun Yatai. Beijing Guoan manager
Roger Schmidt named Guo as number one in the rest of the season. He played 22 matches in his debut season and won
2018 Chinese FA Cup title with Guoan. On 3 December 2018, Guo extended his contract with the club until the end of 2023. On 4 February 2026 Guo Quanbo announced his retirement from professional football via his social media. ==International career==