Bethell unsuccessfully contested election to the
House of Commons for the
Tooting constituency in the
2005 general election, losing to Labour candidate and future Mayor of London
Sadiq Khan. Bethell contested the
2009 primary to become the
Conservative Party's
prospective parliamentary candidate for the
constituency of
Gosport. He came second behind
Caroline Dinenage, who went on to become the
Member of Parliament in the
2010 general election.
House of Lords Bethell entered the
House of Lords in July 2018, after successfully contesting a Conservative
hereditary peers' by-election. He had succeeded to the title of
Baron Bethell following his father's death in 2007, but hereditary peers have not had an automatic right to a seat in the Lords since the
House of Lords Act 1999. In July 2019, he was appointed a
Lord-in-Waiting and, in March 2020, was appointed as
Parliamentary Under-Secretary of State for Innovation at the
Department of Health and Social Care in the
second Johnson ministry. In November 2020,
The Times reported Bethell's appointment as the Minister for
NHS Test and Trace, formed as part of the
Johnson ministry's efforts to control the
COVID-19 pandemic. As minister, his responsibilities included life sciences, medicines, research, international diplomacy and relations, data and technology, and NHS security management, including cyber security. As the House of Lords health minister, he was responsible for representing health matters and legislation in the Upper House, and he moved the Coronavirus Bill at Third Reading and the Medicines and Medical Devices Bill at Second Reading in the Lords. As the junior minister supporting the health track of the United Kingdom’s G7 presidency, he took part in related health-policy work during the UK’s 2021 presidency. In July 2021, he was one of the ministers associated with the publication of the government's Life Sciences Vision, a ten-year strategy for the sector. According to
The Times, Bethell "was a surprise appointment in March having chaired
Matt Hancock's leadership campaign in 2019 and giving [him] a £5,000 donation." He became the subject of allegations of "cronyism" published in
The Guardian over his selection to an advisory role of lobbyists like
George Pascoe-Watson, whose clients include the
Boston Consulting Group "which has won several large government contracts during the pandemic." In July 2021, Bethell was placed under investigation by the
House of Lords Commissioner for Standards over a "complaint regarding Lord Bethell sponsoring a pass for Gina Coladangelo", who was a lobbyist and lover of the then Health secretary
Matt Hancock. In August 2021, it was reported that Bethell had replaced his mobile phone earlier that year and not transferred data from his previous phone, meaning that it could not be searched for messages related to an £85m contract with
Abingdon Health that was subject to judicial review. In November 2021 he stated in a witness statement that three prior explanations he had given for why he could not access his messages – that he lost his phone, that his phone was defective and that he had given it to a relative – were incorrect and that he had deleted them because he incorrectly thought they were backed up. On 17 September 2021, Lord Bethell left government during the second
cabinet reshuffle of the
second Johnson ministry. In November 2021, it emerged that Lord Bethell had been part of a government meeting regarding a £600 million contract with
Randox, the clinical diagnostics firm for which
Owen Paterson was found to have breached parliamentary standards in which, against protocol, no minutes were taken. In 2022 and 2023, he joined the Development Council of
Sadler's Wells, and became Board Advisor to
Plessey Semiconductors, Senior Advisor to the
Milken Institute, and Board Member of Business for Health, a UK-based business-led coalition focused on workplace health and prevention. He has also served on the House of Lords
Secondary Legislation Scrutiny Committee and as vice-chair of the All-Party Parliamentary Groups on Health and Swimming. In June 2023, Bethell appeared on
BBC Radio 4 to defend the government which was trying to prevent disclosure of Boris Johnson's WhatsApp messages to the COVID-19 inquiry and stated that no decisions were made in WhatsApp groups during the pandemic. In December 2023, after
Michelle Mone admitted her involvement in PPE Medpro, Bethell posted a screenshot of a text message that Mone had sent him in 2020. In March 2026, shortly after the
House of Lords (Hereditary Peers) Bill was passed by both houses of parliament, Bethell wrote online that he was looking forward "to leaving the life of a parliamentarian". Since leaving ministerial office, Bethell has continued to hold roles in health policy and public life. He co-hosts the podcast
Prevention is the New Cure with former health minister
Steve Brine, a programme in which the two former health ministers discuss health and politics. Bethell serves as Senior Counsel to Oviva UK Limited, a digital health company providing weight-management services in partnership with the NHS, including programmes involving GLP-1 weight-loss medication. He is a non-executive director of Regenerus Labs, a UK-based diagnostics company that provides functional and diagnostic testing services. He is a trustee of the
Royal Society for Public Health, an independent UK health charity. He is a Senior Visiting Fellow in the Department of War Studies at
King's College London. According to an official government advisory-appointments letter, the role has included research on the national-security implications of developments in the life sciences, including the dual-use risks of genomic research collaboration with China. ==Personal life==