Main •
Rachel True as Mona Rose Thorne. The elder of the two sisters and daughter of Phyllis Thorne and Charles Thorne. Mona was primarily raised by Phyllis and grew up resenting Dee Dee for having their father's attention and growing up in a privileged household. As the series progresses, the two become closer and Mona enjoys her role as Dee Dee's big sister. She is cynical, insecure, and prone to impulsive decisions. •
Essence Atkins as Deirdre Chantal "Dee Dee" Thorne, Esq. The younger of the two sisters and daughter of Big Dee Dee LaFontaine Thorne and Charles Thorne. She grew up to be a bossy, materialistic, fashion-savvy woman like her mother, but slowly matures to become a more well-rounded individual under Mona's influence. Throughout the series, she studies at law school and eventually becomes a sports agent. •
Telma Hopkins as Phyllis Thorne. The mixed-race mother of Mona Thorne and the ex-wife of Charles Thorne. She is loving, but overbearing. Being a psychiatrist, she is prone to meddling in Mona's life and often gives advice to Mona and her friends. She has a contentious relationship with Big Dee Dee and initially thinks the worst of Dee Dee as well. As the series progresses, she serves as mother figure for Dee Dee and occasionally gets along with Big Dee Dee. •
Valarie Pettiford as Deirdre "Big Dee Dee" LaFontaine Thorne. The mother of Dee Dee Thorne and Drew Christian Thorne and the current wife of Charles Thorne. She is a superficial fashionista, who can be controlling and prone to dramatics. However, she cares deeply about Dee Dee and eventually blooms to care for Mona as well, often offering advice to the both of them. She has an on-going rivalry with Phyllis, although the two occasionally call a truce. •
Chico Benymon as Andre "Spencer" Williams. Mona's best friend and co-worker, whom she's known since college. The two briefly date throughout the series, but remain on good terms. •
Alec Mapa as Adam Benet. Mona's openly gay assistant who is very nosy and gossipy. He often hits on Spencer and insults Mona on her unfashionable appearance.
Recurring •
MC Lyte as Kai Owens, Mona's boss •
Obba Babatundé as Charles Thorne, Mona and Dee Dee's father; ex-husband of Phyllis and current husband of Big Dee Dee. •
Estelle Harris as Sophie, Mona's grandmother (and Phyllis' mother), who is white and Jewish. •
Corey Holcomb as Chauncey, Spencer's cousin •
Joey Lawrence as Brett Mahoney •
Coby Bell as Glen Stallworth •
Keith Robinson as Neil Crawford •
Michelle Williams as Naomi Dawson • Penny Bae Bridges as Young Mona • Gabby Soleil as Young Dee Dee •
Yvette Nicole Brown as Ceci •
Louis Gossett Jr. as Ray Willis, Spencer's father. •
Suzy Nakamura as Tina •
Lamman Rucker as Chase • Charles Divins as Lorenzo •
Rowena King as Camille ==Episodes==