•
Allan Hancock (1875–1965), heir to Rancho La Brea, developer of Hancock Park, Los Angeles •
Clarence E. Hancock (1885–1948), politician of New York, namesake of the Syracuse Hancock International Airport •
Cornelia Hancock (1839–1926), nurse during the American Civil War •
Emerson Hancock (born 1999), baseball player •
George Allan Hancock (1875–1965), Californian oil magnate •
Greg Hancock (born 1970), motorcycle speedway rider •
H. Irving Hancock (Harrie Irving Hancock) (1868–1922), writer, mainly for children •
Hank Hancock (1936-2024), politician •
Harris Hancock (1867–1944), mathematician •
Henry Hancock (1822–1883), landowner in Southern California, owner of Rancho La Brea •
Herbie Hancock (born 1940), jazz musician •
James Hughes Hancock (1931–2020), Judge of the United States District Court for the Northern District of Alabama •
John Hancock (1737–1793), American Revolutionary; signatory to the United States Declaration of Independence •
Jordan Hancock (born 2003), American football player •
Josh Hancock (1978–2007), pitcher for the St. Louis Cardinals •
Keith Hancock (musician) (born 1980), music educator, Grammy award winner •
Levi W. Hancock (1803–1882), pioneer of Church of Jesus Christ of Latter-day Saints (Mormons) •
Luke Hancock (born 1990), basketball player •
Mary Louise Hancock (1920–2017), New Hampshire politician and activist •
Mel Hancock (1929–2011), U.S. Congressman from Missouri, best known for Missouri's Hancock Amendment •
Michael Hancock (Colorado politician) (born 1969), Mayor of Denver, Colorado •
Phil Hancock (1953–2024), professional golfer •
Tom Hancock (1948–2016), politician from Iowa •
Tommy Hancock (1929–2020), musician •
Trenton Doyle Hancock (born 1974), artist •
Vincent Hancock (born 1989), Olympic shooter •
Winfield Scott Hancock (1824–1886), Union general during the American Civil War ==People from Australia==