MacDonald was a professional accompanist in Europe and the United States. She was a founding member of the Norma Trio, and toured with
Constance Balfour's concert company. In 1910, she opened a piano studio in Dallas. She taught music classes according to the Dunning system, and held leadership positions in the Texas Music Teachers' Association. She also taught classes on the Dunning system to teachers in Cleveland, Chicago,
Albuquerque, New Mexico, and
Little Rock, Arkansas. MacDonald conducted concerts of the Dallas Schubert Club, and organized concerts by European and American musical acts, including
Albert Spalding,
Rosa Ponselle,
Mischa Elman,
Sergei Rachmaninoff and
John Philip Sousa. == Personal life ==