Upon her graduation at the end of 1902, Mayo took up a position as a resident medical officer at the
Adelaide Hospital. There she worked as a clinical clerk at the
Hospital for Sick Children in Great Ormond Street, London. In 1906, Mayo returned to Adelaide and started a private practice in premises owned by her father on
Morphett Street, next to the family home. With spare time on her hands, she began laboratory work at the Adelaide Hospital and took up an appointment as honorary
anaesthetist at the
Adelaide Children's Hospital. Later that year, after hearing a talk about the success of a school for mothers in London, she and
Harriet Stirling (the daughter of
Edward Stirling) founded the School for Mothers in Adelaide. The Kindergarten Union made a room in its offices available for one afternoon a week, where a nurse would weigh babies and Mayo and Stirling would give advice. moving it to
Woodville and renaming it the Mareeba Hospital, Mayo played a central role in establishing Mareeba Hospital and forming its policy, serving as honorary physician, and as honorary responsible officer from 1921 to 1946. Mareeba eventually became a 70-bed hospital, complete with a surgical unit and a ward for premature babies. She used her experiences as a clinical bacteriologist at the Adelaide Hospital as the basis for her thesis, which she was forced to write on the weekends, such was the volume of her workload. She retired in 1938 and became an honorary consulting physician at the Children's Hospital, but when the Second World War broke out, she returned to the hospital as senior paediatric adviser, at the same time organising the Red Cross donor transfusion service.), author of
ABC of Mothercraft, was appointed medical officer for MBHA in 1937. She was a daughter of industrialist and politician
A. Wallace Sandford. == Other activities ==