After completing his fellowship, Klassen was a senior stem cell researcher at the
Children's Hospital of Orange County, where he researched retina-derived stem cells. He then moved to the Singapore Eye Research Institute before joining the Department of Ophthalmology at the
University of California, Irvine (UCI), where he works as a professor. He is also the director of the Stem Cell and Regeneration Program at UCI. On 2012, Klassen co-founded jCyte, a biotech firm focused on creating
Stem-cell therapy for retinal disorders. As the company's president, he guides efforts to translate research from the lab to clinical applications.
Research focus Klassen's lab focuses on the practical application of human retinal progenitor cells (hRPCs) as treatment options for degenerative retinal conditions, especially retinitis pigmentosa. His studies have demonstrated that the transplantation of retinal progenitor cells can enhance photoreceptor function in deteriorating retinas. The stem cell treatment jCell, created by jCyte, has received
Orphan drug status from both the
Food and Drug Administration (FDA) and the
European Medicines Agency (EMA). This status allows the company to access several advantages, such as protections for intellectual property, tax benefits, and funding opportunities. Furthermore, jCell has been included in the Therapeutics for Rare and Neglected Diseases (TRND) program, which is affiliated with the
National Center for Advancing Translational Sciences (NCATS) at the
National Institutes of Health (NIH).
Academic distinctions • Innovator Awards, Awarded Entrepreneurial Leader of the Year 2023 == Personal life==