Early career Perpetuo started his professional MMA career in 2005 and mainly fought in Brazil, most notably Shooto Brasil. He amassed a record of 17–3 prior to being signed by the UFC. Perpetuo faced Tommy Depret for the
Shooto Middleweight Championship on August 25, 2013, at Shooto Brasil 42. He won the bout by unanimous decision.
Ultimate Fighting Championship Perpetuo made his UFC debut replacing
Santiago Ponzinibbio against
Jordan Mein on April 19, 2014, at
UFC on Fox 11. He lost the bout via split decision. Perpetuo faced
Tim Means on July 26, 2014, at
UFC on Fox 12. He lost the bout by unanimous decision and was released by the promotion on October 19, 2015.
Post-UFC career Perpetuo made his return to Shooto Brasil on July 31, 2016, at Shooto Brasil 65 against Cleber Souza. He won the bout by first-round technical knockout. Perpetuo faced Raimundo Chaves on May 11, 2018, at Shooto Brasil 83. He won the bout by TKO in the first round. Perpetuo face Marcão Santana on December 9, 2018, at Shooto Brasil 89. He won the bout by submission in the first round. In his
ONE Championship debut, Perpetuo faced Hiroyuki Tetsuka at
ONE Championship: Century Part 2 on October 13, 2019. He lost the bout by unanimous decision. Perpetuo faced
Elias Theodorou at Prospect Fighting Championships 12 on December 6, 2019. He lost the fight in the third round via TKO. Perpetuo faced
Yukinari Tamura on November 23, 2023, at Shooto Brasil 120. He defended the welterweight title by TKO in the first round. Perpetuo relinquished the Shooto Welterweight title on November 3, 2025 due to injury, ending his reign as the title's longest-reigning holder. As a result, Ryuichiro Sumimura, who had been interim champion since July, was promoted to undisputed champion. ==Championships and accomplishments==