It is likely that HPNS cannot be entirely prevented but there are effective methods to delay or change the development of the symptoms. Slow rates of compression, or adding stops to the compression, have been found to prevent large initial decrements in performance. There is circumstantial evidence suggesting that a high chamber temperature can aggravate HPNS, and that the temperature should be maintained at a comfortable level. Including other gases in the
heliox helium–oxygen mixture, such as
nitrogen (creating
trimix) or
hydrogen (producing
hydreliox), suppresses the neurological effects. Alcohol, anesthetics, and anticonvulsant drugs have had varying results in suppressing HPNS in animals. None are in use for humans. ==In popular culture==