Overview All of the main characters carried over from the previous series, with the exception of director of surgery and chief executive officer
Henrik Hanssen (
Guy Henry), who left the hospital to return to Sweden. Staff nurse Chantelle Lane (
Lauren Drummond) left in episode 5. Long-serving
Chrissie Williams (
Tina Hobley) left in episode 6. New chief executive officer and director of surgery, neurosurgeon Guy Self (
John Michie) joined as of episode 7 followed quickly by director of nursing Colette Sheward (
Louise Delamere) in episode 8. Both
Antoine Malick (
Jimmy Akingbola) and his son, Jake Patterson (Louis Payne) left in episode 7. Junior doctor Gemma Wilde (
Ty Glaser) departed in episode 10, along with general surgeon
Michael Spence (
Hari Dhillon), who left for an "extended break from the series". Consultant anesthetist Edward Campbell (
Aden Gillett) left the show after episode 13. Both Dominic Copeland (
David Ames) and Adele Effanga (
Petra Letang) arrived in episode 14, Ames having appeared as a recurring character in the previous series. Raffaello "Raf" di Lucca (
Joe McFadden) arrived in episode 16. Raf's wife, Amy Teo (Wendy Kweh) also joined the team as consultant pharmacist on AAU from episode 24. Bonnie Wallis (Carlyss Peer) was killed off on her wedding day in episode 25. Jesse Law (
Don Gilet) joined the team as a consultant anesthetist on Keller from episode 28 then left in episode 39. Adrian Fletcher arrived in episode 44. Essie Harrison (Kaye Wragg) arrived in episode 30 then left in episode 47. Sam Stockman reprised his role as Elliot's son, James Hope in episode 41, having previously appeared as a recurring character between 2006 and 2007.
Main characters •
Jimmy Akingbola as
Antoine Malick (until episode 7) •
Chizzy Akudolu as
Mo Effanga •
David Ames as
Dominic Copeland (from episode 14) •
Camilla Arfwedson as
Zosia March •
Bob Barrett as
Sacha Levy •
Paul Bradley as
Elliot Hope •
Louise Delamere as
Colette Sheward (from episode 8) •
Hari Dhillon as
Michael Spence (until episode 10) •
Lauren Drummond as
Chantelle Lane (until episode 5) •
Aden Gillett as
Edward Campbell (until episode 13) •
Ty Glaser as
Gemma Wilde (until episode 10) •
Tina Hobley as
Chrissie Williams (until episode 6) •
Jules Knight as
Harry Tressler •
Petra Letang as
Adele Effanga (from episode 14) •
Rosie Marcel as
Jac Naylor •
Joe McFadden as
Raf di Lucca (from episode 16) •
Niamh McGrady as
Mary-Claire Carter (until episode 28, from episode 52) •
John Michie as
Guy Self (from episode 7) •
Rob Ostlere as
Arthur Digby •
Hugh Quarshie as
Ric Griffin (until episode 23, episodes 43−49) •
Catherine Russell as
Serena Campbell •
Michael Thomson as
Jonny Maconie •
Alex Walkinshaw as
Fletch (from episode 44)
Recurring and guest characters • Jotham Annan as Nathan Hargreave (until episode 4) • Tom Beard as Jeremy Solis (episodes 14−16) •
Don Gilet as
Jesse Law (episodes 28−39) •
Ben Hull as
Derwood "Mr T" Thompson •
Wendy Kweh as
Amy Teo (from episode 24) •
Amanda Mealing as
Connie Beauchamp (episode 42) •
Alan Morrissey as Kyle Greenham (from episode 50) • Louis Payne as Jake Patterson (episodes 1−7) • Carlyss Peer as
Bonnie Wallis (until episode 25) •
Sam Stockman as James Hope (episode 41) •
Kaye Wragg as
Essie Harrison (episodes 30−47) •
Sandra Voe as Adrienne McKinnie ==References==