The show relies on
Kathy Griffin's stand-up in the first part of the program. Kathy's mother Maggie Griffin, and Kathy's assistant Tiffany Rinehart, both seated in the front row of the audience, are then introduced. The main parts of the show feature a panel of "civilians" (random people, staff, or friends) and sometimes celebrities, chatting about hot issues of the week. The next part of the show is a pre-recorded segment involving comedic antics Kathy has done during the week. Finally, Maggie gives her opinions on topics and the night's events in a segment called "Maggie Tucks Us In". In season 2, the set of the show was re-decorated. It was revealed that the studio of the show, Studio 58, used to be the studio of
The Late Late Show with Craig Ferguson before it moved to Studio 56. Also, the panelists consist mostly of celebrities rather than "civilians". The segment "Maggie Tucks Us In" has been cut; however, Maggie Griffin, along with Rinehart is still seated in the audience each episode and Kathy would occasionally chat with them. ==Episodes==