Pendexter began his career as a humorous writer; some of this early work was anthologised in
Mark Twain's book series,
Library of Humor. Pendexter's main body of fiction consisted of historical novels and
Westerns for such publications as
Adventure and
Argosy. Pendexter was known for his detailed research when writing fiction; his stories were "often accompanied with extensive reading lists of the books that were used in writing the story". For
Short Stories magazine, Pendexter wrote a series of mystery stories featuring "Jeff Fanchon, Inquirer". Fanchon was a Manhattan-based detective of partial Native American ancestry. For the same publication Pendexter created deliberately comical Western stories about Hiram Polk, The Shorthorn Kid. Pendexter's
Red Trails and
The Shadow of the Tomahawk revolve around the struggle between frontiersmen and Native Americans during
Dunmore's War. Pendexter's novel,
Kings of the Missouri about
fur trading and the founding of
St. Louis, is regarded by some critics as his best work. == Bibliography ==