The HNRCA is one of the largest research centers in the world studying nutrition and physical activity in healthy and active aging and the prevention of age-related disease. It has made significant contributions to U.S. and international nutritional and physical activity recommendations, public policy, and clinical healthcare. These contributions include advancements in the knowledge of the role of dietary calcium and
vitamin D in promoting nutrition and bone health, the role of nutrients in maintaining the optimal immune response and prevention of infectious diseases, role of diet in prevention of cancer, obesity research, modifications to the Food Guide Pyramid, contribution to USDA nutrient data bank, advancements in the study of
sarcopenia, heart disease, vision, brain and cognitive function, front of packaging food labeling initiatives, and research of how genetic factors impact predisposition to weight gain and various health indicators. == Center structure==