Soto made his pro debut at the age of 17 and accumulated a record of 36-5-2, which included a 14 fight undefeated streak, before challenging for his first major title.
Featherweight On August 20, 2005, Soto won the interim
WBC Featherweight title by beating
Rocky Juarez, in a fight which he accepted on two weeks notice. On January 17, 2006, Soto defended his interim title by knocking out
Oscar León in the 9th round. He vacated his interim featherweight title and defeated
Ivan Valle in a
WBC Super Featherweight title eliminator bout. On January 22, 2007, Soto defeated
Humberto Toledo (30-2-2) by third-round knockout. In his next bout, he defeated
Bobby Pacquiao by seventh-round knockout. On November 17, 2007, Soto fought reigning
WBO Super Featherweight champion
Joan Guzmán but lost the bout by unanimous decision.
Soto vs. Guzman On November 17, 2007, Humberto Soto fought WBO Junior-Welterweight champion Joan Guzman. The Dominican champion dominated the fight based on his speed of hands, reflexes, and superior boxing skills, effectively counter punching the relentless attack of Soto, who showcased tremendous strength, courage and determination. Guzman won the bout by Unanimous Decision.
Super Featherweight Soto vs. Lorenzo On June 28, 2008, Soto faced off against
Francisco Lorenzo (33-4, 14 KOs) for the vacant interim
WBC Super Featherweight title. Soto knocked Lorenzo down twice in the fourth round with a barrage of punches. However, after lengthy consultations with officials at ringside, referee
Joe Cortez disqualified Soto for hitting Lorenzo after he was down in what appeared to be a grazing punch. Cortez's decision was widely criticized and the WBC refused to award Lorenzo the title. WBC president
José Sulaimán condemned the decision as a "gross injustice" and one of the biggest he has seen in a long time. Sulaiman also announced that the WBC board of governors will vote on whether to declare the fight a no contest or to declare Soto the winner by knockout. Lorenzo, therefore, was not presented the green WBC belt as its champion, since it, though, opted to ignore the official verdict, and declared the title vacant. Sulaiman stated he wasn’t seeking to overrule the decision, but: "While we respect the authority of the (Nevada commission) for a decision of the fight, we are the only ones to have the authority to decide on the decision relating to the WBC world title." On October 11, 2008, Soto defeated
Gamaliel Díaz to win the interim
WBC Super Featherweight title by technical knock out. Soto knocked Diaz down in the first round and dominated him throughout the bout. Diaz was docked two points for excessive holding and his corner refused to send him out for the eleventh round. On December 20, 2008, Soto captured the vacant
WBC Super Featherweight Championship with a 12-round unanimous decision over
Francisco Lorenzo in a rematch of their controversial bout. Lorenzo was repeatedly warned for low-blows and headbutting throughout the bout. Lorenzo was docked one point in the 7th round for headbutting and another in the 8th for excessive holding. The final scores were 117-109 from two of the judges and 118-108 on the other card in favor of Soto. In 2009, Soto successfully defended his WBC Super Featherweight title 3 times. On December 12, 2009, Soto moved up to the lightweight division and defeated former two-time champion
Jesús Chávez by a 10-round unanimous decision.
Lightweight On March 13, 2010, Soto claimed the WBC Lightweight Championship by defeating
David Diaz. Soto dropped Diaz in the opening and final rounds en route to a unanimous decision victory. On May 15, 2010, Soto made his first title defense against
Ricardo Dominguez. Soto won the fight with a 12-round unanimous decision with the judges scoring the fight, 118-110 on two of the scorecards and 117-112 on the other one for Soto. Soto and
Urbano Antillon staged a stirring world lightweight title bout at the
Honda Center. Soto, relying on his ability to strike the challenger with barrages, made his third successful title defense by outlasting Maywood's Antillon in a close unanimous decision, December 4, 2010.
Super Lightweight In July 2011 Soto relinquished his WBC Lightweight Title in anticipation of competing in the junior welterweight division. A bout between hard-hitting Argentinian junior welterweight and Soto has been confirmed for late April. Soto is riding a 14-bout winning streak that includes six knockouts.
Soto vs. Sollano On June 23, 2012 Humberto Soto faced hard-hitting junior welterweight Lucas Matthysse. dropped Soto in the fifth round. Soto's corner stopped the bout between the rounds. ==Professional boxing record==