He was born in the village Kafr al-Garayda in
Gharbiyya on 2 November 1910 to a family of landowners. His father had studied in the French school in
Tanta and was a member of parliament in 1924, 1925 and 1931. He graduated from Wassiya primary school in 1922 and the Sa'diya secondary school in 1926. He later attended law school in
Cairo University, graduating in 1931 and went to work in the
Niyaba, leaving briefly following the death of his father in 1934 to manage the family estates. During his post-graduate career, he was briefly an apprentice to
Hassan Allam. He first ran in the
1936 parliamentary elections representing his hometown district as a Wafd candidate with the help of leading Wafdist
Makram Ebeid. He became a financial advisor to the wife of the leader of the party,
Mustafa al-Nahhas, and received his first ministerial position following the Wafdist victory in the
1942 elections. Following Ebeid's falling out with al-Nahhas, Ebeid would accuse Serageddin of corruption, a charge he denied. He would also serve as interior minister in Nahhas' government. He sponsored a law giving Egyptian trade unions legal recognition for the first time and was elected honorary president of Wafd friendly unions in Cairo and Alexandria. In September 1944,
King Farouk was infuriated to see banners with his name and al-Nahhas and ordered them removed, which the director of public security complied without consulting Serageddin, who fired him. Shortly afterwards, al-Nahhas' government was dismissed. Out of power, he managed his estates, successfully ran for
senate in 1946 and served on the board of directors of the Egyptian Coca Cola Company. He helped organize Wafdist protesters during the
1946 Egyptian protests. He later became secretary of the Wafd part in June 1948. He served as minister of communication in
Hussein Sirri Pashas' government in 1949. == Late Wafd career ==