I-459 begins at a trumpet interchange with I-20/I-59 near Bessemer and McCalla. Exit 1, an interchange with Eastern Valley Road, provides access to the large Colonial Promenade shopping center and
McCalla community. The freeway then passes under Pocahontas Road and next to the Bent Brook Golf Club before intersecting with Morgan Road at exit 6. Morgan Road connects with
Bessemer,
Helena, and the western fringes of Hoover along with the
Bessemer Airport. After Morgan Road, I-459 enters a much more populated and developed area, namely the large suburb of
Hoover. Once interchanging with
State Route 150 (SR 150) at exit 10, the highway turns northeastward and widens to 10 lanes. Exit 13 is with
US 31, a major suburban route through Hoover,
Vestavia Hills, and
Pelham. A southbound flyover ramp at this interchange provides direct access to the
Riverchase Galleria. The freeway then approaches its interchange with I-65, one of two four-level stack interchanges in the state (the other being its interchange with I-20). After the I-65 interchange, the roadway decreases to six lanes and has a minor interchange with Acton Road at exit 17. As it exits Hoover, I-459 intersects with
US 280, an 8- to 10-lane suburban
arterial that is one of the most congested roads in
Greater Birmingham. The area around this interchange contains many hotels and office buildings. After the US 280 interchange, it turns north and enters a residential area along the
Cahaba River, crossing the river twice before passing the "Miss Liberty" (
Statue of Liberty replica) and the exit 23 interchange with Liberty Parkway and Overton Road. The highway passes east of
Mountain Brook while turning northeast and interchanging with Grants Mill Road at exit 27. After this intersection, I-459 turns northward again as it approaches the suburb of
Trussville. The interchange with I-20 is one of two
stack interchanges in Greater Birmingham. In its last few miles, the highway intersects with Derby Parkway and
US 11 in Trussville before completing its course with an interchange at I-59. ==Future==