State Road 165 starts at State Road 66 near
Wadesville then goes north through
Poseyville where it intersects
Interstate 64 at Exit 12. It is also concurrent with State Road 68 for about a mile in Poseyville. It then continues north before going east, ending at its parent route, State Road 65, at the
Owensville town square. Like many State Highways in the area SR 165 often sees heavy coal truck traffic as it also provides a shortcut between the mines around Owensville and Princeton and the Port of Indiana in
Mount Vernon. ==Major intersections==