Inverted papilloma

Inverted papillomas are definitively diagnosed by histologic examination. However, magnetic resonance imaging (MRI) may show a characteristic feature described as a convoluted cerebriform pattern (CCP). A retrospective study published in the American Journal of Neuroradiology concluded that identification of CCP by MRI in a patient with a nasal tumor made the diagnosis of Inverted papilloma quite likely. The study reported the sensitivity and specificity to be 100% and 87% respectively. CCP can be associated with other malignant tumors as well. ==Treatment==

The treatment of choice in sinus and nose is by Functional endoscopic sinus surgery. == Recurrence and malignification ==

Inverted papillomas of the sinus and nose have a high risk of recurrence after surgical treatment. The recurrence often occurs within 2 years after the surgery and at the initial anatomical site . Inverted papillomas have a potential for malignant transformation in 5-15%. == History ==

Inverted papillomas were first described by Nils Ringertz in 1938. He reported their microscopic appearance and their tendency to grow into the connective tissue stroma. ==Additional image==

File:Bladder inverted papilloma histopathology (1).jpg|Histopathology representing an inverted papilloma of the urinary bladder that was cystoscopically resected. Hematoxylin and eosion stain. File:Bladder inverted papilloma histopathology (2).jpg|Histopathology representing an inverted papilloma of the urinary bladder that was cystoscopically resected. Hematoxylin and eosion stain. File:Bladder inverted papilloma histopathology (3).jpg|Histopathology representing an inverted papilloma of the urinary bladder that was cystoscopically resected. Hematoxylin and eosion stain. File:Inverted Schneiderian Papilloma of the Nasal Cavity (8116183976).jpg|Inverted Schneiderian Papilloma of the Nasal Cavity. File:Inverted Schneiderian Papilloma of the Nasal Cavity (8116184172).jpg|Inverted Schneiderian Papilloma of the Nasal Cavity with Abundant intraepithelial microabscesses. == References ==