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Iproheptine

Iproheptine, also known as N-isopropyl-1,5-dimethylhexylamine or N-isopropyloctodrine and sold under the brand names Metron and Susat, is a nasal decongestant which has been marketed in Japan. It is described as a vasoconstrictor and antihistamine. The drug is available over-the-counter in Japan.

Pharmacology
Pharmacodynamics Iproheptine is described as a decongestant, vasoconstrictor, and antihistamine. The drug was found to have anticholinergic- and antihistamine-like effects that were described as more potent than those of ephedrine. Pharmacokinetics In contrast to arylalkylamines like phenethylamines and tryptamines, iproheptine is not metabolized by monoamine oxidase (MAO). ==Chemistry==
Chemistry
Iproheptine, also known as N-isopropyl-1,5-dimethylhexylamine or as N-isopropyloctodrine, is an alkylamine and the N-isopropyl derivative of octodrine (2-amino-6-methylheptane or 1,5-dimethylhexylamine (1,5-DMHA)). ==History==
History
Iproheptine was first described in the scientific literature by 1960 and was first patented by 1962. It remained marketed in Japan in 2004. ==Society and culture==
Society and culture
Names Iproheptine is the generic name of the drug and its . In the case of the hydrochloride salt, its generic name is iproheptine hydrochloride and this is its . The drug is marketed under the brand names Metron and Susat (both as the hydrochloride salt). Availability Iproheptine appears to have been marketed only in Japan. It is available over-the-counter in this country. ==See also==
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