Isabella Bartholomew Mears was a British physician who worked as a medical missionary and translator of Chinese philosophy. Born in West Lothian, Scotland, she trained at the London School of Medicine for Women, becoming the twenty-fifth woman listed on the British Medical Register. She served with the Church Missionary Society (CMS) in Foochow (Fuzhou), China from 1890 to 1893. The couple founded Woodburn Sanatorium in 1895, one of the earliest Scottish sanatoria dedicated to tuberculosis care. She also published translations and interpretations of Chinese philosophical texts, including Tao Teh King and Creative Energy.