MarketIsothiouronium
Company Profile

Isothiouronium

In organic chemistry, isothiouronium is a functional group with the formula [RSC(NH2)2]+ (R = alkyl, aryl) and is the acid salt of isothiourea. The H centres can also be replaced by alkyl and aryl. Structurally, these cations resemble guanidinium cations. The CN2S core is planar and the C–N bonds are short.

Synthesis
Salts comprising these cations are typically prepared by alkylation of thiourea: :SC(NH2)2 + RX → [RSC(NH2)2]+X− ==Reactions==
Reactions
Hydrolysis of isothiouronium salts gives thiols. :[RSC(NH2)2]+X− + NaOH → RSH + OC(NH2)2 + NaX Isothiouronium salts in which the sulfur has been alkylated, such as S-methylisothiourea hemisulfate (CAS number: 867-44-7), will convert amines into guanidinium groups. This approach is sometimes called the Rathke synthesis after Bernhard Rathke who first reported it in 1881. : RNH2 + [CH3SC(NH2)2]+X− → [CH3N(H)C(NH2)2]+X− + CH3SH Chelating resins with isothiouronium groups are used to recover mercury and other noble metals including platinum from solutions. ==References==
tickerdossier.comtickerdossier.substack.com