Ajax Van der Wiel started his playing career at
RKSV DCG in Amsterdam. At age seven, the young defender was scouted by
AFC Ajax and brought to the Ajax Academy at "De Toekomst". Talking about his period at Haarlem, Van der Wiel has said, "When I was there I realized how spoiled I was. At Ajax everything was always well organized. We received a new kit every season and were picked up with minivans and brought to the club. At Haarlem I arrived in a totally different world. The accommodation was much worse, we played in five-year-old outfits, and had to find our own way to the trainings. The atmosphere was better though, much more relaxed than at Ajax. The period at Haarlem was good for my social development. It was a wake-up call for me." Following the departure of youth captain
Donovan Slijngard, Van der Wiel was made captain of
Jong Ajax. He would play three more matches that season. At the end of the 2006–07 season, Van der Wiel signed a four–year contract with the club, keeping him until 2011. At the start of the 2007–08 season, Van der Wiel participated in the 1–0 victory over
PSV in the battle for the
Johan Cruyff Shield, resulting in winning his first career trophy. In a 1–0 win over
Dinamo Zagreb in the first round of the
UEFA Cup on 20 September 2007, his performance was praised by manager
Henk ten Cate. A knee injury kept him out for most of the 2007–08 season. In the
2008–09 season, Van der Wiel managed to recovered from the knee injury ahead of the new season and hoped to succeed
John Heitinga, who departed for
La Liga side
Atlético Madrid over the summer. After returning from injury, Van der Wiel regained his first place at the club, playing in the right-back position. At one point, he played in the midfield position due to midfielder crisis. His performances resulted in him signing a contract extension with the club on 28 January 2009, lasting until 2013. He then scored his first goal for the club on 1 March 2009 in a 2–0 win over
Utrecht. For his performance in the 2008–09 season, he was awarded AFC Ajax's Talent of the Year. His performance attracted interests from
Premier League side
Manchester City. On 24 January 2010, he scored his fourth goal of the season in a 1–0 win over AZ. He, once again, helped the club keep six clean sheets between 3 February 2010 and 7 March 2010. Van der Wiel played as a right–back in both legs of the
2009–10 KNVBCup final, as the club beat Feyenoord 4–2 to win the tournament. For his performances during the season, he was awarded the Johan Cruijff Award for "
Young Player of the Year." Following the
2010 World Cup, Van der Wiel was in talks to transfer to
Louis van Gaal's
Bayern Munich. However, Ajax was not able to agree to a deal. The 2010–11 season was another successful season for Van der Wiel, as he maintained his first-team position under new manager
Frank de Boer. Despite some setbacks, Van der Wiel continued to regain his first team place at right-back. After being linked with a move to Manchester City and
Barcelona in the January transfer window, he ended the transfer speculation by declaring his intention to stay at the club. In the final of the
KNVB Cup against FC Twente, he started the match in the right–back and played 91 minutes before being substituted, as the club lost 3–2. During the 2011–12 season, Van der Wiel suffered a groin injury on two occasions, which affected his season. He returned to training after two months sidelined. Ahead of the
2012–13 season, Van der Wiel continued to be linked a move away from Ajax, and he made it clear he was not keen on signing a new contract with Ajax in January 2012. He missed the
Johan Cruyff Shield, After a 5–0 win over
NAC Breda on 25 August 2012, in what was his last appearance for Ajax, Van der Wiel hinted at his departure from the club. His departure became imminent after Ajax agreed to sell Van der Wiel to French
Ligue 1 club
Paris Saint-Germain.
Paris Saint-Germain in the
UEFA Champions League match Van der Wiel moved to Paris Saint-Germain on 1 September 2012 for a reported €6 million transfer fee. The move was confirmed two days later, when he was issued the number 23 shirt and signed a four-year contract lasting until 2016. Van der Wiel made his PSG debut on 22 September 2012 in an away match against
Bastia, a 0–4 victory; Van der Wiel played the full 90 minutes at right-back. For the most part of his debut season in France, Van der Wiel would come off the substitutes' bench for PSG
captain Christophe Jallet, the team's first-choice
right-back. Van der Wiel made his European debut for Paris in the
2012–13 UEFA Champions League match against
Porto, a 1–0 away loss, with Van der Wiel being substituted off for Jallet in the 66th minute. Van der Wiel scored his first PSG goal in the 0–4 away win against
Toulouse, the final goal of the match. On 12 May 2013, PSG became champions of France, winning the
2013–14 Ligue 1 title in a 1–0 victory against
Lyon at home, marking the club's third ever national championship. Van der Wiel remained on the substitutes' bench for the duration of the title-winning fixture. At the start of the
2013–14 season, Van der Wiel was linked a move away from the club, as Italian
Serie A club
Internazionale were interested in signing him. Although a transfer never materialized, he remained at the club and found himself in competition with Christophe Jallet at right-back. As a result, Van der Wiel and Jallet often rotated in the position. Towards the end of the season, he suffered injuries on two occasions. He earned first-team status at PSG and saw him included in the ''L'Equipe'' Team of the Year for 2013. At the start of the
2014–15 season, Van der Wiel played the entire match in the
Trophée des Champions, a 2–0 PSG win over
Guingamp. After Christophe Jallet's transfer to Lyon, Van der Wiel continued to feature at right-back, although he faced a new competition from new signings
Serge Aurier and
Jordan Ikoko, which often forced him to the substitutes' bench. By season's end, Van der Wiel helped PSG win the domestic
treble:
Ligue 1,
Coupe de France and the
Coupe de la Ligue. In the
2015–16 season, Van der Wiel regularly found himself on the substitutes' bench, behind Serge Aurier and
Marquinhos at right-back. He also faced with his own injury concerns in the first half of the season. For the third time, he helped the club win the domestic
Treble:
Ligue 1,
Coupe de France and the
Coupe de la Ligue. On 15 May 2016, it was officially announced Van der Wiel would be leaving PSG at the end season after his contract expired. This was announced after he acknowledged it would be difficult to stay at the club.
Fenerbahçe After leaving Paris Saint-Germain, Van der Wiel signed for Turkish team
Fenerbahçe, signing a three-year contract with an option to extend for an additional year. Upon joining the club, he was joined up by compatriot
Robin van Persie. Van der Wiel made his official debut for Fenerbahçe on 27 July 2016 in the third qualifying round of
UEFA Champions League, where he set up a goal for
Emmanuel Emenike in a 2–1 home win over
Monaco. However, in the second-leg, the club was eliminated from the competition following a 3–1 away defeat. He then made his Fenerbahçe debut on 21 August 2016 in the opening match of the
2016–17 Süper Lig season, where he started the entire match in a 1–0 loss to
İstanbul Başakşehir. His lack of first-team opportunities at the club led manager
Dick Advocaat to be keen on selling him in January, although a transfer was never agreed and he remained at the club until the end of the season. For Fenerbahçe, Van der Wiel made 12 league appearances and 17 across all competitions.
Cagliari After only one season with Fenerbahçe, on 25 August 2017, Van der Wiel joined Italian club
Cagliari. In so doing, he became the first Dutchman to ever sign for the club. He was issued the number 2 shirt by the Sardinian side. He made his debut in a 3–2 home loss to
Genoa on 15 October, having missed the first six matches of the season through injury. However, after returning from injury, he still struggled to earn playing time during the first half of the season, making only six appearances across all competitions. Upon joining the club, he was issued the
number 9 shirt during an introductory press conference. He made his club debut on 3 March in the opening match of the MLS season, a 2–0 home defeat to
Columbus Crew. Despite suffering from setbacks that saw him on the sidelines, Van der Wiel established himself in the starting eleven for the side. He then played in both legs of
2018 CONCACAF Champions League Final against
Chivas Guadalajara, as Toronto eventually lost the final 4–2 in a penalty shoot-out after the series was tied 3–3 on aggregate. During the season, Van der Wiel played in several different positions for the side, such as centre-back, left-back, and right-midfield. But most of the season, he played in the right-back position. During a preseason training session in Los Angeles on 23 January 2019, Van der Wiel was dismissed after an altercation with coach
Greg Vanney. On 22 March 2019, he was released by the club by mutual consent. On 6 August 2020, Van der Wiel began training with
Eredivisie club
RKC Waalwijk. Shortly after, he reiterated that he wanted to continue playing football, having been a free agent for a year. ==International career==