Enang became a councillor in 1987 and a member of the Akwa Ibom State House of Assembly in 1992. He was elected to the House of Representatives in 1999. He served three terms as a member of the House of Representatives. His election to represent the Itu/Ibiono Ibom Federal Constituency in April 2007 was nullified in December 2007 by an Election Petition Tribunal sitting in
Uyo. He was eventually reelected on 20 January 2010. Enang worked toward the abolition of the onshore/offshore dichotomy, ensuring that his state of Akwa Ibom became the highest earner of oil revenue in the country. As the federal representative for Itu/Ibiono, Enang was appointed Chairman of the House Committee on Business and Rules. In April 2011, Enang contested for the Senate seat of Uyo (North-East) on the
Peoples Democratic Party (PDP) platform and won with 160,942 votes. The runner-up was Nsima Edem Umoh of the
Action Congress of Nigeria (ACN) with 121,965 votes. Enang served as the Senior Special Assistant to President Muhammadu Buhari on National Assembly Matters (Senate) from 27 August 2015 to 29 May 2019 and later on Niger Delta Affairs, following a letter of appointment dated 14 August 2019, which took effect from 29 May 2019. He resigned in May 2022 to pursue his governorship ambition under the
All Progressives Congress (APC) but failed to secure the party's ticket for the election. ==References==