The brewery was formed in 1828 when retired cotton manufacturer John Lees purchased land in
Middleton, Lancashire and built Greengate Brewery, from which the company still operates. His grandson, John William Lees, took over the company in 1876. The Greengate Brewery was rebuilt in 1876. The business was re-incorporated in 1955 when
R.W.T. Lees-Jones bought the share capital of the company back under single ownership. The company is still family owned and operated. When William, Simon, Christina, Anna and Michael Lees-Jones joined Richard and Christopher at J.W. Lees in the 1990s, they were the sixth generation from the founder to work in the company. In 2023 Louis Lees-Jones joined the company as the first member of the seventh generation of the family to work at J.W. Lees, opening Founder's Hall in February 2024. In 2003
HRH Charles, Prince of Wales visited to celebrate the brewery's 175th anniversary. and in 2018 The Governor Lager was added to the range. Also in 2018, the company announced a collaboration with physicist
Brian Cox, an amber ale entitled Cosmic Brew. In 2018, the brewery converted the old boiler house on site into a microbrewery in order to create more experimental small barrelage productions. In 2019, J.W. Lees won Best Brewing Pub company at the publican awards. In 2025, J.W. Lees was granted exclusive brewing rights of Boddingtons Cask. The cask version of
Boddingtons was last brewed in 2012 by Hyde's Brewery. The beer closely matches the original version which was brewed by Boddingtons themselves at Strangeways Brewery. Boddingtons closed their brewery in 2005 and was subsequently demolished and replaced by a car park. ==Beers==