From 1995 to 2002, he worked at
The Second City and
IO Theater in Chicago, McBrayer appeared in over 80 sketches on ''
Late Night with Conan O'Brien (2002–04), often lampooning his own Southern upbringing by playing stereotypical hillbilly characters. On August 10, 2007, and September 20, 2008, he made cameo appearances on Late Night
playing Kenneth Parcell from 30 Rock''. During the first appearance, O'Brien remarked to him, "I thought you were above this now." McBrayer later reprised his role as Kenneth twice (November 24, 2009, and January 13, 2010) after O'Brien's switch to
The Tonight Show. He appeared on O'Brien's
Legally Prohibited From Being Funny on Television Tour at stops in
Eugene, Oregon,
Universal City, California (on the
Universal Studios lot where O'Brien taped
Tonight), and the final tour stop in
Atlanta. In 2008, he was featured throughout the video for "
Touch My Body" by
Mariah Carey. McBrayer said he accidentally hit Carey in the face with a
Frisbee during the shooting for the video. He worked as a voice actor in the American animated series
Ugly Americans and has voiced
Irving DuBois on
Phineas and Ferb since 2009. In 2010, he played a role in
Cats & Dogs: The Revenge of Kitty Galore. He regularly appears in the skit "Knock Knock Joke of the Day" on the hit children's television show,
Yo Gabba Gabba! since season 2 and stars in
Craig McCracken's TV show
Wander Over Yonder on the Disney Channel. In 2011, he also appeared in
The Simpsons, in the season 22 episode, "
The Great Simpsina" as Ewell Freestone, 'Peach Guy.' In 2012, McBrayer lent his voice to the Disney animated film
Wreck-It Ralph, playing the title character's video game opponent and eventual friend Fix-It Felix Jr. In 2013, he starred alongside
Los Angeles Clippers player
Blake Griffin in
Kia commercials, and appeared in a commercial for
Barnes & Noble. McBrayer's
Adult Swim series
The Jack and Triumph Show premiered in February 2015. In September 2016, on the season 10 premiere episode of
The Big Bang Theory, McBrayer played Penny's older brother Randall. In 2018, McBrayer was one of the actors who voiced the audiobook
A Day in the Life of Marlon Bundo. In December 2018, it was announced McBrayer would make his
West End stage debut in the transfer of the Broadway musical
Waitress, playing the role of Ogie, until June 15, 2019. The production opened at the Adelphi Theatre in London on February 8, 2019. In June 2019, he appeared on ITV's
The Sara Cox Show. In 2020, McBrayer had a recurring role on the
Quibi comedy-mystery series
Mapleworth Murders. In 2021, he appeared as a contestant on a Season 6 episode of the
Netflix baking competition series
Nailed It!. In 2024, he began hosting the show
Zillow Gone Wild on
HGTV. ==Filmography==