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James Hope (physician)

James Hope (1801–1841) was an English physician. He has been called "the first cardiologist in the modern sense". He is known for discovering the early diastolic murmur of mitral stenosis in 1829.

Life
He was born at Stockport in Cheshire 23 February 1801, the son of Thomas Hope, merchant and manufacturer, he of Prestbury Hall near Macclesfield. After four years (1815–18) at Macclesfield grammar school, James resided for about 18 months at Oxford, where his elder brother was then an undergraduate, but never became a member of the university. In October 1820 Hope went as a medical student to Edinburgh University, where he studied for five years. The subject of his inaugural medical dissertation (August 1825) was aneurysm of the aorta, and he then began a collection of drawings of pathological specimens coming under his notice. A president of the Royal Medical Society of Edinburgh, he held the posts of house-physician and house-surgeon at the Edinburgh Royal Infirmary. In 1829 he established a private dispensary linked to the Portman Square and Harley Street district visiting societies. In 1831 he was elected physician to the Marylebone Infirmary, where he had charge of ninety beds. In the autumn of 1832 he delivered at his own home a course of lectures, intended for practitioners only, on diseases of the chest. He afterwards lectured at St. George's Hospital, where he was elected assistant physician in 1834, and at the Aldersgate Street School of Medicine. ==Works==
Works
In 1829 Hope began to publish a series of papers, building up to a projected work on the heart. Four papers on Aneurysms of the Aorta, based on Observations as House Physician and House Surgeon to the Royal Infirmary, Edinburgh, appeared in the London Medical Gazette, 1829, and in 1830 he sent to the same journal four papers relating especially to the sounds of the heart and the physiology of its action. He also wrote for the Cyclopædia of Practical Medicine about the same time the articles "Aorta, Aneurysm of", "Arteritis", "Dilatation of the Heart", "Heart, Diseases of", "Heart, Degeneration of", "Heart, Hypertrophy of", "Palpitation", "Pericarditis and Carditis", and "Valves of the Heart, Diseases of"; these were not published till 1833–1835. Hope also based a work about morbid anatomy on his own drawings. The first part appeared at the beginning of 1833, and the last at the end of the following year. With articles in medical periodicals, he contributed the article on Inflammation of the Brain to Alexander Tweedie's Library of Medicine. Notes on the Treatment of Chronic Pleurisy was finished days before his death (Medico-Chirurgical Review, vol. xxxv. 1841). ==Family==
Family
Hope married Anne Fulton on 10 March 1831. They had one child, Theodore Hope. ==Notes==
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