Jane Doe is introduced as a serial killer who observes her targets and then kills them before assuming their identity. She first appears disguised as
Arkham Asylum therapist Dr. Anne Carver. When she was about to kill her latest patient
Warren White,
Batman showed up and exposed Doe's identity while White found the real Dr. Carver's body. Guards arrived to contain the situation, but Batman told them to stay back while he spoke to Jane. Jane stated that she wanted to look into the madness of Arkham Asylum by posing as Dr. Carver, and that by compiling her own psychological profile, she has realized that her desire to steal other people's identities is driven by a need to fill an "emptiness" within her. Jane breaks down as the guards take her back to her cell. As the notes taken by Doe as Dr. Carver in the last two months are thrown out,
Aaron Cash confronts Jane about what happened to her. Aware that Cash had feelings for the doctor, Jane comments that she knew Dr. Carver was disgusted by Cash losing his hand to
Killer Croc and that she could never love him. Doe later assumes the identity of an Arkham security guard named Wrigley and escorts Doodlebug to his cell, leaving the door ajar on purpose. Still posing as Wrigley, Doe kidnaps White during a prison riot. After the
Black Glove's failed plan to destroy Batman, Jane Doe and the rest of the inmates from Arkham Asylum were transferred to
Blackgate until Arkham was completely decontaminated. The
second Black Mask organizes a plan of action that involves Doe, Adam Bomb,
Firefly, and the other escaped Arkham patients. When Commissioner
James Gordon visits District Attorney Hampton's office and tries to get an arrest warrant on
Two-Face, Doe breaks into the office, gunning down Hampton and shooting Gordon three times as a "message from Two-Face." She was unaware that Gordon was wearing a bulletproof vest that saved his life. During the "
Brightest Day" storyline, Jane Doe is seen in Arkham Asylum when
Deathstroke's
Titans enter Arkham Asylum to deal with a certain patient. After
Osiris kills a guard, he unknowingly activates a switch that releases all the inmates, thus allowing Jane to escape once again. In 2011, DC Comics rebooted their universe with "
The New 52." Jane Doe appeared at a bank posing as wealthy socialite Vivian Wenner. When her accountant stated that Vivian Wenner is legally dead and cannot access her accounts, a shootout occurs that attracted the attention of Batman. Doe gives Batman the slip and was saved by the villain
Wrath. Wrath then persuades Doe to take a disguise that can enable her to infiltrate the
Gotham City Police Department. When Batman confronts
Harvey Bullock, he deduces that he is not the real Bullock as Doe sheds her disguise. When Doe is weakened by the ensuing fight, she is taken down by psychiatrist Dr. Abigail Wilburn as she and Batman discover the real Bullock locked in the basement. When remanded to Arkham Asylum, Doe chooses Batman as her next target. Harvey later visits Arkham Asylum and learns that Dr. Wilburn is now Doe's appointed psychotherapist In truth, Doe was actually conversing with herself while being observed by Arkham doctors. ==Powers and abilities==