In 1580 a quarrel broke out between the Mackenzies and the
Macdonells of Glengarry. The Chief of Glengarry had inherited part of
Lochalsh,
Lochcarron, and
Lochbroom, from his grandmother, Margaret, one of the sisters and co-heiresses of Sir
Donald Macdonald of Lochalsh, and granddaughter of Celestine of the Isles. Colin's father, Kenneth Mackenzie, had acquired the other part by purchase from Dingwall of Kildun, son of the other co-heiress of Sir Donald, on 24 November 1554, and Queen Mary had confirmed the grant by Royal charter. The friction arising from this close proximity between Mackenzie and Macdonell erupted into an open feud, in the course of which Ruairi Mackenzie of
Redcastle (Colin's brother) invaded Glengarry's lands with 200 men: Macdonell himself was taken prisoner and his three uncles murdered. In 1582 Macdonell complained to the
Privy Council, who, investigating the matter, caused
Strome Castle, which Macdonald yielded to Mackenzie as one of the conditions of his release, to be placed under the temporary custody of the
Earl of Argyll. According to the records of the Privy Council, Kintail himself was detained at
Blackness Castle in open ward to answer such charges as might be brought against him. Whatever Colin's personal involvement in the murders may have been, his relationship with James VI did not fail him and, in 1586, the King granted a remission to "Colin McKainzie of Kintaill and Rodoric McKainzie of Auchterfailie" (
Redcastle), "his brother, for being art and part in the cruel murder of Rodoric McAllester in Stroll; Gorie McAllester, his brother, in Stromcraig; Ronnald McGorie, the son of the latter; John Roy McAllane vic Allester, in Pitnean; John Dow McAllane vic Allester, in Kirktoun of
Lochcarroun; Alexander McAllanroy, servitor of the deceased Rodoric; Sir John Monro in
Lochbrume; John Monro, his son; John Monro Hucheoun, and the rest of their accomplices, under silence of night, upon the lands of Ardmanichtyke, Dalmartene, Kirktoun of Lochcarroun, Blahat, and other parts within the baronies of Lochcarroun, Lochbrume, Ros, and Kessane, in the Sheriffdom of Innerness," and for all their other past crimes. ==Discomfiture of the Earl of Huntly==