Reed was selected in the second round, 50th overall, by the
Green Bay Packers in the
2023 NFL draft. He signed his rookie contract on July 20, 2023. Reed made his NFL debut on September 10, 2023, catching two passes for 48 yards and rushing once for −2 yards in a 38–20 win against the
Chicago Bears. He scored his first two NFL touchdowns on September 17 in a 25–24 loss to the
Atlanta Falcons, on nine- and 10-yard passes from
Jordan Love. In week 18, he had four receptions for 112 yards in a win over the Bears. As a rookie, he appeared in 16 games and started 13. He finished with 64 receptions for 793 yards and eight touchdowns, while also rushing for 119 yards on 11 carries with two touchdowns. In Week 1 of the 2024 season, against the Eagles, Reed had four receptions for 138 yards and a 70-yard receiving touchdown to go with a 33-yard rushing touchdown in the 34–29 loss. In Week 2 of the 2025 season, Reed suffered a fractured collarbone during the first quarter of a
Thursday Night Football game against the
Washington Commanders. The injury happened as Reed was catching a touchdown pass (the touchdown got overturned due to a holding call on right tackle
Anthony Belton) while Commanders safety
Quan Martin fell on Reed's right shoulder, and was expected to be out for 6–8 weeks. On September 17, Reed underwent surgeries to repair a
broken clavicle and a
Jones fracture in his left foot. He was activated from injured reserve on December 6, ahead of the team's Week 14 matchup against the
Chicago Bears. On April 24, 2026, the Packers signed Reed to a three year contract extension worth $50.25 million. ==NFL career statistics==