Father Dufresse was sent as a missionary to
Sichuan (formerly spelled Szechwan, or ), West China in December 1775. In 1776 he left
Macau to go inland and reached Szechwan after more than three months of travel. He was then imprisoned once in Peking and released. As soon as he had learned enough of the Chinese language, Bishop Pottier sent him to the north of the province. At the end of 1784, an anti-Christian persecution broke out. Dufresse was arrested and managed to escape to a friendly Christian house. There he received a note from the coadjutor bishop, Monsignor de Saint-Martin, inviting him to give himself up in order to calm the unrest. He obeyed and left for
Tchen-Tou where he arrived on February 27, 1785, where he was imprisoned for a few weeks before being transferred to Peking with Bishop de Saint-Martin and two other missionaries, Delpon and Devaux. There he underwent many painful interrogations before finally being released on November 9, 1785. One day in 1785, while Dufresse was part of a convoy of prisoners, one of his guards, moved by the faith and patience of the bishop, converted and even became a priest later. He was
Augustine Zhao Rong who was martyred in 1815. The same is true of
Joseph Yuan, who was also converted at that time, was ordained a priest and arrested in 1816 after evangelizing a vast region; he was strangled on June 24, 1817. These two men and more than a hundred others are part of the group of 120 martyrs of China. However, although released, the missionaries were not allowed to return to Sichuan. Dufresse therefore requested permission to go to Macau, hoping to return to his mission lands from there. He was taken to
Canton, where he took a boat to the
Philippines. After a long stay in
Manila, he was finally brought back to Macau by a French ship. From Macau, under very difficult traveling conditions, he finally reached Sichuan on January 14, 1789. ==Bishop==