Mwema played a long time for
Antwerp Giants, as he played in Antwerp from 2009 until 2016. In the 2011–12 season, Mwema was named the
BLB Most Promising Player. In December 2016, Mwema signed a contract with
Telenet Oostende. On 19 February 2017, marked the first time Mwema won a title with his team when he won the
Belgian Cup. Mwema signed a one-year extension with the team on 28 July 2020. In his five seasons with Oostende, he won the
Pro Basketball League (PBL) five consecutive times. On 5 August 2021, Mwema returned to Antwerp Giants for a second stint, signing a contract for three seasons. On 12 March 2023, Mwema and the Giants won the
Belgian Cup after beating
BC Oostende in the final. In August 2024, he signed for
HLA Alicante of the Spanish
Primera FEB. ==International career==