Tvede discontinued his studies to run the distillery when his father died in 1849. He initially ran it on behalf of his mother but became its owner in 1854. The distillery was located in the courtyard at Sudergade 23. It was destroyed in a fire in 1864. He then purchased a new site at Stjernegade 25 and constructed a modern, steam-powered distillery. It grew to considerable size. Inn 1877 he also started a production of
small beer and a yeast factory followed in 1887. Tvede converted his firm into a limited company under the name Helsingør Spritfabrik. Tvede's son Charles Tvede was managing director of the company. Tvede was at the time of his death president of the Danish Destillers' Association (Foreningen af Spiritusfabrikanter i Danmark). ==Other commercial activities==