De Guzman also played in the 2012
Palarong Pambansa and led the
NCR Team to a championship, where she also won the Best Setter award. De Guzman was the setter of the
Philippine team for the
2015 Asian Women's U23 Volleyball Championship and in the
2015 Southeast Asian Games. She was
Ateneo Lady Eagles team captain for the
UAAP Season 79. On May 6, 2017, De Guzman announced that she will not be returning to the
Ateneo Lady Eagles in
UAAP Season 80. She later joined the
Creamline Cool Smashers as part of the team's build up for the inaugural
Premier Volleyball League All-Filipino Conference. She worked as Ateneo Lady Eagles assistant coach during the
Premier Volleyball League 1st Season Collegiate Conference. De Guzman won the most valuable player award in the
2017 Battle of the Rivals. She won the best setter award in the
2017 Premier Volleyball League Open Conference. In 2018, the Creamline Cool Smashers won the championship of the
2018 Premier Volleyball League Reinforced Conference and was awarded best setter and finals' Most Valuable Player. On August 31, 2023, De Guzman signed a deal with the
Denso Airybees of the
Japan V.League Division 1 as their Asian import for the 2023-2024 season. She is the first Filipina setter and the fifth Filipino player to play in the Japan V.League. On her first season overseas, she managed to help Denso Airybees finish fifth in the
2023–24 Japan V.League Division 1 Women, followed by a championship during the 2023–24 Japan V.League Division 1 Women V.Cup. In May 2024, de Guzman became captain of the
Philippines women's national volleyball team, and served in the position until September. The Philippines finished as silver medalists at the
2025 AVC Women's Volleyball Nations Cup. De Guzman was named as the tournament's Best Setter. De Guzman returned to Creamline in January 2026 after three years of absence from the PVL. ==Personal life==