Jiayuguan South railway station is a railway station located in Jiayuguan, Gansu Province, China. It was put into operation on December 26, 2014. It serves the Lanzhou–Xinjiang High-Speed Railway with High Speed services between Lanzhou and Urumqi and conventional services connecting Urumqi to various cities in Eastern and South Western China. It is the second major railway station serving Jiayuguan, with Jiayuguan railway station, which serves the conventional Lanzhou-Xinjiang Railway.