Sullivan was born on April 14, 1866, in
Feeding Hills, Agawam, Massachusetts, United States. The name on her baptismal certificate was Johanna Mansfield Sullivan, but she was called "Anne" or "Annie" from birth. She was the eldest child of Thomas and Alice (née Cloesy) Sullivan, who had emigrated from Ireland to the United States during the
Great Famine. At age five, Sullivan contracted the bacterial eye disease
trachoma, which caused many painful infections and, over time, made her nearly blind. When she was eight, her mother died from
tuberculosis, and her father abandoned the children two years later for fear that he could not raise them on his own. The investigation was led by
Franklin Benjamin Sanborn, then chairman of the board, and
Samuel Gridley Howe, founder of the
Perkins School for the Blind in Boston. In February 1877, Sullivan was sent to the
Soeurs de la Charité hospital in Lowell, Massachusetts, where she had another unsuccessful operation. While there, she helped the nuns in the wards and went on errands in the community until July of that year, when she was sent to the city infirmary, where she had one more unsuccessful operation. She was then transferred back to Tewksbury under duress. Instead of returning to the facility for predominantly ill and insane patients, she was housed with single mothers and unmarried pregnant women. In 1880, during a subsequent inspection of Tewksbury by
Franklin Benjamin Sanborn, now State Inspector of Charities, Sullivan implored of him to allow her to be admitted to the
Perkins School for the Blind, in
Watertown, Massachusetts, when she threw herself in front of him, pleading, “Mr. Sanborn, I want to go to school!” Within a matter of months, that plea was granted. ==Education==