Season 1 Abe '''''' (voiced by
Will Forte) is the clone of
Abraham Lincoln, the 16th
President of the United States. He is the main
protagonist of the first season. Abe is an awkward and clumsy kid who feels he is struggling to live up to the legacy of Abraham Lincoln. He is good friends with Gandhi and Joan, being oblivious to the latter's feelings towards him. He falls for Cleopatra during the first season, only to realize in the last episode of the first season that he is in love with Joan. He spends the second season trying to win her over.
Joan '''''' (voiced by
Nicole Sullivan) is the clone of
Jeanne d'Arc, the devout 15th century
French militant. She is the main protagonist of the second season. She is Abe's closest friend and is in love with him. His constant ignorance of this causes her a lot of frustration. She is a
goth, and somewhat of an outcast at her school. She spends much of the first season trying to win over Abe, to no avail. In the last episode of the first season, she sleeps with JFK at prom after he shares an encouraging conversation with her. She begins dating him in the second season, but they eventually break up, and she admits she never lost feelings for Abe in the season finale. In season 3, she begins to date Confucius, but her feelings become conflicted during the season's finale when she is left on Cloney Island with Abe and Confucius as it is set to be destroyed.
Cleo Cleopatra "
Cleo"
Smith (voiced by
Christa Miller (season 1),
Mitra Jouhari (seasons 2-3)) is the clone of
Cleopatra VII, the last
Pharaoh of
Ancient Egypt. Cleopatra is a stereotypical
mean girl, very vain and rude to those who are not as popular as her. She loses many of these traits by the end of the second season. She had a rivalry with Joan over Abe, which ended after the first season. She is a
bisexual character, dating JFK and Abe in the first season, and Frida Kahlo in the second.
JFK JFK (voiced by
Christopher Miller) is the clone of
John Fitzgerald Kennedy, the 35th President of the United States. JFK is a stereotypical popular high school
jock. He is arrogant, competitive, and at times dimwitted. He initially antagonized Abe in the hopes of winning Cleo back from him, but he befriends him by the end of the second season. JFK dated Joan for a period of time in the second season. He speaks with a thick
New England dialect and
Boston accent that is exaggerated for comical effect, as well as constant insertions of "uh" and "err" into his sentences. He also has a penchant for using
dirty jokes and
innuendo. In 2020, the show had a resurgence in popularity after multiple voice clips of JFK became popular on
TikTok.
Gandhi Gandhi (voiced by
Michael McDonald) is the clone of
Mohandas Karamchand Gandhi, an activist of the
Indian Revolution. Gandhi is a hyperactive and immature teenager who wants to be accepted by those around him. He is close friends with Abe and Joan. He has ADHD. His portrayal as a party animal enraged many in
India, including prominent members of
India's parliament. Hunger strikes at MTV's India headquarters lead to the premature cancellation of the first season of
Clone High. He did not return in the second season, although he is shown to still be frozen as of the second season finale. Gandhi's characterisation as a "
party animal" meanwhile received a negative reception in
India, culminating in a 150-person
hunger strike held outside of
MTV's Indian branch in early 2003, leading to
Clone High consequently being cancelled. While Gandhi did not return in the
2023 revival of Clone High,
Phil Lord stated in March 2023 that while the character would also not appear in either season of the two-season revival, that the character could return if the series was renewed for another season beyond those two.
Principal Scudworth '''''' (voiced by Phil Lord) is a deluded and aggressive scientist. He is the man who created the clones, and he serves as the principal of their school. He is shown to have very little control over his emotions and is prone to violent outbursts. He works for the Secret Board of Shadowy Figures, although he plans to steal the clones from them in order to make his own amusement park, which he dubs "Cloney Island". In the second season finale, he admits that he cares for the clones, and he feels that they are like his children. In the third season, he succeeds in building Cloney Island, capturing the clones and making them work permanent summer jobs. However, the season ends with Cloney Island being on the verge of destruction.
Mr. Butlertron '
(voiced by Christopher Miller), more commonly referred to as Mr. B.', is the loyal robot servant and best friend to Scudworth. He serves as the assistant principal of Clone High. Mr. Butlertron is very human-like, programmed to be
sentient and possesses
artificial intelligence that enables him to show human emotions, have
free will, and have facial expressions. He genuinely cares for Scudworth and the students, often calling people "Wesley."
The Shadowy Figure '
is a ruthless and secretive government organization who employs Principal Scudworth. They are a parody of the CIA. Their ultimate aim is to use the clones for a super army to take over the world. Its chief director is referred to as The Shadowy Figure' (voiced by
Bill Lawrence). He is often annoyed by Scudworth's incompetence in running Clone High. In the season 1 finale, he plans to take the clones away from Scudworth on prom night. This forces Scudworth to freeze everyone in attendance at prom in a meat locker, including the Shadowy Figures, in order to save the clones and himself. In the second season, the original board is replaced by a new board, led by a woman. The new board is later murdered by Scudworth in the second season's finale. It is not clarified if the original board was ever unfrozen from the meat locker.
Seasons 2-3 Candide Sampson Candide Sampson (voiced by
Christa Miller) is Principal Scudworth's strict, cold-hearted superior in season 2. She was put in charge of him by the new Secret Board of Shadowy Figures. Principal Scudworth is shown to have a brief romantic interest in her, before ultimately attacking her in order to save the clones. She is Joan's
foster mother in season 2. In season 3, she becomes the sole member of the Secret Board of Shadowy Figures following their deaths in season 2. She ends up sending a missile to destroy Cloney Island in the season's finale. Miller originally voiced
Cleo in the original
Clone High, before being recast in the role and cast as a new character in the 2023 revival due to retrospective concerns about
whitewashing.
Frida Kahlo Frida Kahlo (voiced by
Vicci Martinez) is the clone of
Frida Kahlo. She is a very laid-back character, and she enjoys painting. She is best friends with Harriet Tubman. She is
queer, as she and Cleopatra begin a romantic relationship.
Harriet Tubman Harriet Tubman (voiced by
Debra Wilson (season 1),
Ayo Edebiri (seasons 2-3)) is the clone of
Harriet Tubman. She is very preppy, and is prone to excessive worrying at times. She is Frida's best friend. She and Confucius begun a relationship in season 2, but they broke up in season 3, with Harriet gaining feelings for Toussaint Louverture. She enters a relationship with Toussaint, but breaks up with him as well, being unhappy with how perfect he is.
Confucius Confucius (voiced by
Kelvin Yu) is the clone of
Confucius. He is obsessed with the internet and various social media trends. He was in a relationship with Harriet, but is now dating Joan of Arc.
Topher Bus Topher Bus (voiced by
Neil Casey) is the clone of
Christopher Columbus, who tries to distance himself from his "clone-father" by pretending to be supportive of social movements and minority groups, as well as changing his name. This is a facade, however, as he reveals his true distaste for said groups on several occasions. == Supporting characters ==