He studied medicine at the
University of Utrecht, and trained as a pathologist in
Amsterdam. During this time he came across the symptoms of what is now known as Pompe's disease, or
Glycogen storage disease type II, which he described in his 1932 publication
Over idiopathische hypertrophie van het hart (English:
About idiopathic hypertrophy of the heart). On December 27, 1930, Dr. Pompe had carried out an autopsy on a 7-month old girl who had died of unknown causes. He found the enlarged heart now known to be characteristic of the infantile form of the disease and had some microscopy slides prepared. These showed that the muscle tissue was distorted into a pentagonal mesh. == Execution by the Nazis ==