Milwaukee Bucks (2009–2010) On April 7, 2009, Meeks declared his eligibility for the
2009 NBA draft and his intention to not hire an agent, leaving open the possibility of returning to Kentucky next season. In a May 28 story, Meeks stated in reference to his desire to be a first round NBA draft pick, "If I'm not first round, then I'll go back to school." On June 15, 2009, Meeks decided to stay in the draft and forgo his final season of eligibility at Kentucky. During the
2009 NBA draft on June 25, 2009, Meeks was drafted 41st overall by the
Milwaukee Bucks. Stuck behind a deep guard rotation, Meeks struggled to receive playing time from Head Coach
Scott Skiles.
Philadelphia 76ers (2010–2012) On February 18, 2010, Meeks was traded to the
Philadelphia 76ers along with
Francisco Elson in exchange for
Primoz Brezec and
Royal Ivey. Meeks finished his rookie season without a start, failing to gain more minutes in then-Sixers coach
Eddie Jordan's rotation than he did in Milwaukee. Entering his second year, Meeks was expected to play a limited role behind Sixers second overall pick
Evan Turner and
Lou Williams, who was the starter the previous season. Through the course of the season, however, he was named the team's starting shooting guard by new Sixers Coach
Doug Collins, as Williams transitioned into a sixth man role. In just his second start, Meeks scored 26 points (20 in the first quarter), shooting 9–16 from the field, including 7–10 from long range (6–7 in the first quarter). Meeks continued as the Sixers starting shooting guard for the
2011–12 season, though he would lose minutes to Evan Turner. On March 27, 2012, Meeks scored 31 points, a new career high.
Los Angeles Lakers (2012–2014) in 2013 On August 13, 2012, Meeks signed a two-year deal with the
Los Angeles Lakers. On November 30, he scored 21 points on a then career-high seven three-pointers in a 122–103 win over the
Denver Nuggets. On March 9, 2014, Meeks scored a career-high 42 points in a 114–110 win over the
Oklahoma City Thunder.
Detroit Pistons (2014–2016) On July 14, 2014, Meeks signed a three-year, $19.5 million contract with the
Detroit Pistons. After missing the first 22 games of the
2014–15 season with a lower back injury, Meeks made his Pistons debut on December 12, 2014, scoring 12 points off the bench in 22 minutes to help his team snap a 13-game losing streak with a 105–103 win over the
Phoenix Suns. On December 30, Meeks scored 34 points on a career-high nine three-pointers in a 109–86 win over the
Orlando Magic. He came within one three-pointer of tying
Joe Dumars' franchise record of ten three-pointers. On October 30, 2015, Meeks was ruled out for 12 to 16 weeks after undergoing a surgical procedure to repair a non-displaced fracture of the fifth metatarsal in his right foot. On April 13, 2016, Meeks made his return on the season finale game against the Cavaliers, collecting 20 points in 26 minutes.
Orlando Magic (2016–2017) On June 29, 2016, Meeks was traded to the
Orlando Magic in exchange for a future conditional second-round draft pick. On July 19, 2016, he underwent surgery to stabilize the fifth metatarsal in his right foot. On September 19, 2016, he was deemed a possibility of returning to action in November. He made his debut for the Magic on December 2, 2016, after the foot injury held him out for the first 19 games of the season. He finished with 10 points and three steals in 17 minutes against the
Philadelphia 76ers. On January 2, 2017, he scored a season-high 23 points in a 115–103 win over the
New York Knicks. On January 19, 2017, he was ruled out for four to six weeks after dislocating the thumb on his shooting hand. An MRI exam revealed Meeks had two sprained ligaments in his right thumb. He underwent surgery to repair his right thumb five days later. He returned to action on March 20, 2017, playing against the
Philadelphia 76ers after missing 26 games.
Washington Wizards (2017–2018) in 2018 On July 12, 2017, Meeks signed with the
Washington Wizards. On April 13, 2018, he was suspended without pay for 25 games for violating the terms of the NBA/NBPA anti-drug program, testing positive for
ipamorelin and
GHRP-2. On October 15, 2018, Meeks was traded, along with a future second-round draft pick and cash, to the
Milwaukee Bucks in exchange for a future second-round draft pick. Meeks' league-mandated suspension for violating the NBA/NBPA anti-drug program ended on November 24, leading to the Bucks waiving him the following day.
Toronto Raptors (2019) On February 20, 2019, Meeks signed a 10-day contract with the
Toronto Raptors. He was not signed to a second 10-day contract after the first expired. On March 26, he returned to the Raptors, signing with the team for the rest of the season. On March 30, 2019, he scored a season-high 14 points to go along with 5 rebounds in a 124–101 road win against the Bulls. Meeks was part of the Raptors team that defeated the two-time defending champion
Golden State Warriors in the
2019 NBA Finals and after six games, he became an NBA champion.
Raptors 905 (2022) On January 10, 2022, Meeks signed with the
Raptors 905 of the
NBA G League. He was waived on March 18. ==National team career==