As a
true freshman in 2014, Iyiegbuniwe played in the first three games of Western Kentucky's season before a knee injury ended his season. He elected to take a medical
redshirt. In 2015, as a redshirt freshman, Iyiegbuniwe played in all 14 of Western Kentucky's games, recording 19 tackles and one
sack. In 2016, Iyiegbuniwe, now a redshirt sophomore, once again appeared in all 14 games. He made 64 tackles (10 for loss), 3.5 sacks, three pass deflections and one forced fumble. He was awarded 2016 C-USA Honorable Mention. As a redshirt junior in 2017, Iyiegbuniwe played in all 13 games, recording 117 tackles (11.5 for loss), two sacks, one pass deflection and three forced fumbles. He was named to the 2017 C-USA First-team. After the season, he declared for the
2018 NFL draft. ==Professional career==