In 1977, Keithley, along with
Chuck Biscuits' older brother, started a band called
the Skulls. After the breakup of the Skulls, Keithley formed D.O.A. with Biscuits. In 2004, he published the autobiography
I, Shithead: A Life in Punk. He was inducted into the Canadian Independent Music Hall of Fame the same year. Keithley appeared in the punk/cult film
Terminal City Ricochet, as well as contributing music (through D.O.A.) to the soundtrack. He and D.O.A. appeared in
Bruce McDonald's 1995 cult film
Hard Core Logo. He was interviewed for a documentary titled
Let's All Hate Toronto, produced by Elevator Films and published by
The Disinformation Company. In 2006, Keithley was featured prominently in the feature-length documentary
American Hardcore. During D.O.A.'s 2011 Canadian tour, in three of the 10 cities where D.O.A appeared, Keithley gave free solo acoustic performances in support of the
Occupy Wall Street protests, namely
Occupy Ottawa,
Occupy Regina and
Occupy Vancouver. He owns and operates his own record company,
Sudden Death Records. The recording company was started in 1978 as a DIY response to lack of interest from major labels. His motto is 'TALK-ACTION=ZERO.' ==Politics==