American •
John Clark (Delaware governor) (1761–1821), American governor and farmer of Delaware •
John Clark (Georgia governor) (1766–1832), American politician and governor of Georgia •
John Clark (Minnesota politician) (c. 1825–1904), Minnesota state senator •
John Clark (Utah politician) (1834–1908), mayor of Salt Lake City, Utah •
John Bullock Clark (1802–1885), American politician and U.S. representative from Missouri and Confederate congressman •
John Bullock Clark Jr. (1831–1903), American politician and U.S. representative from Missouri •
John C. Clark (1793–1852), American politician and U.S. representative from New York •
John Davidson Clark (1884–1961), American lawyer, member of the Council of Economic Advisers (1946–1953) •
John E. Clark (politician) (1910–2003), American politician and judge •
John F. Clark, ninth director of the United States Marshals Service •
John Gee Clark (1890–1984), member of the California legislature •
John M. Clark (1821–1902), Sheriff of Suffolk County, Massachusetts •
John S. Clark (1892–1960), Illinois politician •
John T. Clark, American politician and civil engineer from New York
Canadian •
John Clark (Canadian politician) (1835–1896), Scottish-born politician in Ontario, Canada •
John Arthur Clark (1886–1976), Conservative member of the Canadian House of Commons •
John Etter Clark (1915–1956), member of the Legislative Assembly of Alberta, 1952–1959
Other •
John Allworth Clark (1846–1932), Australian politician - mayor of Brisbane •
John Clark (Roundhead) (fl. 1650s), English member of parliament and colonel in Cromwell's army •
John Harrison Clark (c. 1860–1927), Cape Colony adventurer who ruled much of southern Zambia •
John Clark (Australian politician) (1907–1984), sat in the South Australian House of Assembly ==Science and academics==