Marable practiced
medicine and moved to Yellow Creek, Tennessee, where he continued to engage in the practice, and served as Postmaster, Yellow Creek, Montgomery County, Tennessee. He owned slaves. He was a member of the
Tennessee Senate in 1817 and 1818. He elected alderman for the city of Clarksville, Tennessee in 1819, and was a Charter Member of the Medical Association in Tennessee. Marable was elected as a
Jacksonian Republican to the
Nineteenth and
Twentieth Congresses, serving from March 4, 1825 to March 3, 1829. He was an unsuccessful candidate for re-election to the
Twenty-first Congress, and resumed his practice. ==Death==